Fmoc-allo-Thr-OH

Basic Information

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CAS Number

146306-75-4

Molecular Formula

C19H19NO5

Molecular Weight

341.36 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

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O=C(N[C@H](C(=O)O)[C@@H](O)C)OCC1c2ccccc2c2c1cccc2

InChI

InChI=1S/C19H19NO5/c1-11(21)17(18(22)23)20-19(24)25-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16-17,21H,10H2,1H3,(H,20,24)(H,22,23)/t11-,17-/m0/s1

InChIKey

OYULCCKKLJPNPU-GTNSWQLSSA-N

LogP

2.3590999999999998

Topological Polar Surface Area

95.86000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 6

Synonyms & References

English

L-Allothreonine,N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
Fmoc-L-allo-threonine
Fmoc-Thr-OH
N-[(9-Fluorenylmethoxy)carbonyl]-L-allo-threonine
FMOC-ALLO-THR-OH
FMOC-THR(ALLO)-OH
Fmoc-allo-L-Thr-OH
FMOC-L-ALLO-THR-OH
FMOC-ALLO-THREONINE
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-ALLO-THREONINE
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-ALLO-L-THREONINE
Fmoc-allo-Thr-OH

MDL Number

MFCD01318739

FAQ

What is Fmoc-allo-Thr-OH (CAS: 146306-75-4)?

Fmoc-allo-Thr-OH, also known as N-Fmoc-α-allo-threonine, is a protected amino acid derivative used in solid-phase peptide synthesis. It has the chemical formula C15H20N2O5. This compound is characterized by its high solubility in water and its ability to form amide bonds under mild conditions.

What are the main uses of Fmoc-allo-Thr-OH (CAS: 146306-75-4)?

Fmoc-allo-Thr-OH is primarily used in the synthesis of peptides and proteins for research and pharmaceutical purposes. It is also used as a building block in the development of new drugs and in the preparation of protected amino acid derivatives for solid-phase synthesis.

Is Fmoc-allo-Thr-OH (CAS: 146306-75-4) safe?

Fmoc-allo-Thr-OH is generally considered safe when handled properly. However, it is important to follow all safety guidelines, including wearing appropriate personal protective equipment (PPE) such as gloves and goggles, and ensuring good ventilation. Spills should be cleaned up promptly, and the compound should be stored away from flammable materials.

How should Fmoc-allo-Thr-OH (CAS: 146306-75-4) be stored?

Fmoc-allo-Thr-OH should be stored in a cool, dry place at room temperature, preferably between 15-25°C, and protected from light. It should be kept in a tightly sealed container to prevent moisture absorption. Avoid storing it in humid or high-temperature environments to maintain its stability and efficacy.