5-Methyluridine

Basic Information

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CAS Number

1463-10-1

Molecular Formula

C10H14N2O6

Molecular Weight

258.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

182.0 to 186.0 deg-C

Density

1.5760

Refractive Index

1.618

Specific Rotation

-8.0 to -10.0° (c=2, H2O)

SMILES

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CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O

InChI

InChI=1S/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s1

InChIKey

DWRXFEITVBNRMK-JXOAFFINSA-N

LogP

-2.5434799999999993

Topological Polar Surface Area

124.78 Å²

Hydrogen Bond Donor/Acceptor

4 / 8

Complexity

409

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

b-D-Ribofuranoside thymine-1
5-Methyluridine, powder
BP-58644
DS-18476
Q425078
1-beta-delta-Ribofuranosylthymine
Uridine, 5-methyl-
beta-delta-Ribofuranoside
Ribosylthymine
1-[(4S,2R,3R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,3-dihydropyrimidine-2,4-dione
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione
38T
.beta.-D-Ribofuranosylthymine
1-.beta.-D-Ribofuranosylthymine
PD099507
2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-.beta.-D-ribofuranosyl-
THYMINE RIBOSIDE [MI]
beta-D-Ribofuranoside
Ribothymidine
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
DTXSID20163348
5-Methyluridine, 97%
M1405
SCHEMBL29298
5MU-5MU-5MU
.beta.-D-Ribofuranoside, thymine-1
1463-10-1
beta-delta-Ribofuranoside thymine-1
AM83947
CS-W010160
CHEBI:45996

MDL Number

MFCD00006535

Customs Code

2934999090

FAQ

What is 5-Methyluridine (CAS: 1463-10-1)?

5-Methyluridine is a modified nucleoside with the chemical formula C9H12N2O5. It consists of uracil base attached to a ribose sugar molecule, featuring a methyl group at the 5th carbon position. This compound is known for its stability and is commonly used in biochemical research and pharmaceutical applications. Its structure makes it a key component in RNA studies and drug development.

What are the main uses of 5-Methyluridine (CAS: 1463-10-1)?

5-Methyluridine (CAS: 1463-10-1) is primarily used in pharmaceuticals for antiviral drug development, in research for RNA modification studies, and in biotechnology for synthesizing nucleic acids. It also finds applications in food additives as a flavor enhancer and in industrial processes involving nucleoside-based compounds. Its role in molecular biology makes it essential for studying gene expression and RNA structure.

Is 5-Methyluridine (CAS: 1463-10-1) safe?

5-Methyluridine (CAS: 1463-10-1) is generally considered safe when handled properly, with low toxicity in controlled environments. However, it may cause mild irritation upon contact or inhalation. Safety precautions include wearing gloves and protective eyewear, and following standard laboratory protocols. It is important to consult safety data sheets (SDS) for comprehensive handling guidelines.

How should 5-Methyluridine (CAS: 1463-10-1) be stored?

5-Methyluridine (CAS: 1463-10-1) should be stored in a cool, dry, and dark place, ideally at 2-8°C. Keep it in a sealed container to prevent moisture and contamination. Avoid exposure to light and air to maintain stability. Proper storage ensures its integrity for pharmaceutical, research, or industrial use.