1-(1-Methyl-3-piperidinyl)methanamine

Basic Information

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CAS Number

14613-37-7

Molecular Formula

C7H16N2

Molecular Weight

128.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

58°C/6mm

SMILES

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CN1CCCC(C1)CN

InChI

InChI=1S/C7H16N2/c1-9-4-2-3-7(5-8)6-9/h7H,2-6,8H2,1H3

InChIKey

KEDTYNCWGSIWBK-UHFFFAOYSA-N

LogP

0.28690000000000004

Topological Polar Surface Area

29.259999999999998 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

Safety Information

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Hazard Statement

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

1-methyl-3-piperidinemethanamine
1-(1-Methylpiperidine-3-yl)methanamine
(1-methylpiperid-3-yl)methylamine
PB34157
SCHEMBL1010140
SY097374
3-aminomethyl-1-methylpiperidine
DTXSID60546434
AC-4769
MFCD07757606
AS-30580
3-(Aminomethyl)-1-methylpiperidine
AKOS000210362
3-(aminomethyl)-1-methylpiperidine, AldrichCPR
[(1-methylpiperidin-3-yl)methyl]amine
3-(aminomethyl)-1-methyl-piperidine
1-methyl-3-aminomethylpiperidine
n-methyl-3-(aminomethyl)piperidine
MFCD11226132
KEDTYNCWGSIWBK-UHFFFAOYSA-N
14613-37-7
(1-methylpiperidin-3-yl)methanamine
A808454
F2147-0147
3-piperidinemethanamine, 1-methyl-
SY321008
1-methyl-3-aminomethyl-piperidine
5-amino-1-methyl-indolin-2-one
MFCD06738902
c-(1-methyl-piperidin-3-yl)-methylamine
C-(1-methylpiperidin-3-yl)methylamine

MDL Number

MFCD06738902

FAQ

What are the physical and chemical properties of 1-(1-Methyl-3-piperidinyl)methanamine (CAS: 14613-37-7)?

1-(1-Methyl-3-piperidinyl)methanamine is a colorless to pale yellow liquid with a molecular weight of approximately 174.29 g/mol. It has a pKa of about 8.9 and a pKb of 5.1. The compound is moderately soluble in water and ethanol but less soluble in hexane. It is reactive, particularly under basic conditions, and can undergo hydrolysis and substitution reactions.

How is 1-(1-Methyl-3-piperidinyl)methanamine (CAS: 14613-37-7) typically synthesized?

1-(1-Methyl-3-piperidinyl)methanamine is typically synthesized by the amidation of 1-methyl-3-piperidinemethanol with methanamine in the presence of a suitable base, such as triethylamine. The reaction is carried out under reflux conditions, and the product is then purified by recrystallization or distillation. The yield is generally around 85-90%.

What industries use 1-(1-Methyl-3-piperidinyl)methanamine (CAS: 14613-37-7)?

1-(1-Methyl-3-piperidinyl)methanamine is used in the pharmaceutical industry for the synthesis of certain medicinal compounds. It is also used in the polymer industry as a modifier and in the electronics industry for the production of sensors and semiconductors.

What precautions should be taken when handling 1-(1-Methyl-3-piperidinyl)methanamine (CAS: 14613-37-7)?

When handling 1-(1-Methyl-3-piperidinyl)methanamine, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The substance should be handled in a well-ventilated area, and fume hoods should be used to minimize inhalation risks. Spills should be cleaned up immediately using appropriate methods, and the Material Safety Data Sheet (MSDS) should be consulted for detailed emergency and handling procedures.