5-Carboxy-2'-deoxyuridine

Basic Information

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CAS Number

14599-46-3

Molecular Formula

C10H12N2O7

Molecular Weight

272.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Boiling Point

°Cat760mmHg

Refractive Index

1.639

SMILES

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C1C(C(OC1N2C=C(C(=O)NC2=O)C(=O)O)CO)O

InChI

InChI=1S/C10H12N2O7/c13-3-6-5(14)1-7(19-6)12-2-4(9(16)17)8(15)11-10(12)18/h2,5-7,13-14H,1,3H2,(H,16,17)(H,11,15,18)/t5-,6+,7+/m0/s1

InChIKey

GAGYTXTVUMXAOC-RRKCRQDMSA-N

LogP

-2.1244999999999985

Topological Polar Surface Area

141.85 Å²

Hydrogen Bond Donor/Acceptor

4 / 9

Complexity

461

Synonyms & References

English

CHEBI:102485
A930096
1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid
5-PYRIMIDINECARBOXYLIC ACID, 1-(2-DEOXY-.BETA.-D-ERYTHRO-PENTOFURANOSYL)-1,2,3,4-TETRAHYDRO-2,4-DIOXO-
1-(2-DEOXY-.BETA.-D-ERYTHRO-PENTOFURANOSYL)-1,2,3,4-TETRAHYDRO-2,4-DIOXO-5-PYRIMIDINECARBOXYLIC ACID
5-carboxy-2-deoxyuridine
1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylicacid
MFCD22495153
2'-Deoxy-5-carboxyuridine
5-Carboxy-2'-deoxyuridine
1-((2R,4S,5R)-4-HYDROXY-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL)-2,4-DIOXO-PYRIMIDINE-5-CARBOXYLIC ACID
Q27179272
UNII-TP4HBV9HED
14599-46-3
5-CDURD
1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid
SCHEMBL21113982
TP4HBV9HED
1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidine-5-carboxylic acid
Trifluridine Related Compound A
5-Pyrimidinecarboxylic acid, 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,2,3,4-tetrahydro-2,4-dioxo-
uridine, 5-carboxy-2'-deoxy-
5-Carboxy-2′-deoxyuridine
1-(2-Deoxy-beta-D-erythro-pentofuranosyl)-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinecarboxylic acid
5-Carboxy-2'-dU
TRIFLURIDINE RELATED COMPOUND A (20 MG) (5-CARBOXY-2'-DEOXYURIDINE)
Trifluridine Related Compound A (10 mg) (5-Carboxy-2'-deoxyuridine)
1-(2-Deoxy-β-D-erythro-pentofuranosyl)-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinecarboxylic acid

MDL Number

MFCD22495153

FAQ

What regulatory guidelines apply to 5-Carboxy-2'-deoxyuridine (CAS: 14599-46-3)?

The regulatory guidelines for 5-Carboxy-2'-deoxyuridine (CAS: 14599-46-3) include GHS classification, REACH regulations, and FDA/EPA requirements. This compound is classified as a chemical under the Globally Harmonized System of Classification and Labeling of Chemicals (GHS). For REACH, it is important to comply with the registration, evaluation, authorization, and restriction of chemicals. FDA and EPA regulations may apply due to its use in research and potential biological applications.

Are there alternatives to 5-Carboxy-2'-deoxyuridine (CAS: 14599-46-3) in synthesis?

Yes, there are alternatives to 5-Carboxy-2'-deoxyuridine (CAS: 14599-46-3) in synthesis. Common alternatives include 2'-deoxyuridine and its analogs, such as 5-bromodeoxyuridine (BrdU). These alternatives are often used as substitutes in biological and chemical research due to their structural similarities and functional properties.

What is the market or research trend for 5-Carboxy-2'-deoxyuridine (CAS: 14599-46-3)?

The market and research trends for 5-Carboxy-2'-deoxyuridine (CAS: 14599-46-3) are driven by its applications in cell biology, DNA replication studies, and antiviral research. There is a growing interest in its use as a research tool for studying DNA damage and repair mechanisms. Additionally, its potential use in biomedical research and diagnostics is being explored, which could lead to increased demand in the future.

How should waste containing 5-Carboxy-2'-deoxyuridine (CAS: 14599-46-3) be handled?

Waste containing 5-Carboxy-2'-deoxyuridine (CAS: 14599-46-3) should be handled carefully to ensure environmental safety. Collect waste liquids in appropriate containers and store them separately. Incineration or professional waste disposal services should be used for disposal. Environmental protection measures include proper handling to prevent soil and water contamination. Compliance with local waste management regulations is essential.