4-Amino-5-fluoro-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone | CAS No. 145986-26-1

4-Amino-5-fluoro-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone

Basic Information

CAS Number

145986-26-1

Molecular Formula

C8H10FN3O3S

Molecular Weight

247.25 g/mol

AD

Basic Physical Properties

C1C(OC(S1)CO)N2C=C(C(=NC2=O)N)F

InChI

InChI=1S/C8H10FN3O3S/c9-4-1-12(8(14)11-7(4)10)5-3-16-6(2-13)15-5/h1,5-6,13H,2-3H2,(H2,10,11,14)/t5-,6-/m1/s1

InChIKey

XQSPYNMVSIKCOC-PHDIDXHHSA-N

LogP

-0.45500000000000024

Topological Polar Surface Area

90.37 Ų

Hydrogen Bond Donor/Acceptor

3 / 6

Complexity

374

Synonyms & References

English

  • 4-Amino-5-fluoro-1-[(2RS,5RS)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
  • 3F3F7L71JJ
  • 4-amino-5-fluoro-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
  • SCHEMBL6362885
  • .alpha.-L-Oxathiolanyl-5-fluorocytidine
  • rel-4-Amino-5-fluoro-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
  • alpha-L-(+)-(2R,5R)-5-Fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine
  • 5-epi Emtricitabine
  • RACEMIC TRANS-EMTRICITABINE [WHO-IP]
  • Oxathiolan 5FC-.a.
  • 4-Amino-5-fluoro-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
  • 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, trans-(+/-)-
  • DTXSID30163233
  • 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2R-trans)-
  • alpha-L-Oxathiolanyl-5-fluorocytidine
  • 9NWD5Z8Q3A
  • 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-
  • .alpha.-L-(+)-(2R,5R)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
  • alpha-L-FTC
  • J-008178
  • Oxathiolan 5FC-alpha
  • 146726-77-4
  • NCGC00346561-01
  • 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, rel-
  • 4-Amino-5-fluoro-1-((2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
  • 145986-26-1
  • CHEMBL292175
  • 2(1H)-Pyrimidinone,4-amino-5-fluoro-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-
  • Α-L-(+)-(25R)-5-FLUORO-1-(2-(HYDROXYMETHYL)-1,3-OXATHIOLAN-5-YL)CYTOSINE
  • 4-amino-5-fluoro-1-((2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one

FAQ

What is 4-Amino-5-fluoro-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone (CAS: 145986-26-1)?

4-Amino-5-fluoro-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone is an organic compound with the CAS number 145986-26-1. It is a heterocyclic compound containing a pyrimidine ring with an amino group, a fluorine atom, and a thiol group. This compound has a molecular formula of C10H11FN2O3S and is used in pharmaceutical research for its potential therapeutic applications.

What are the main uses of 4-Amino-5-fluoro-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone (CAS: 145986-26-1)?

4-Amino-5-fluoro-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone is primarily used in pharmaceutical research for its potential as an anti-cancer agent. It is also explored for its anti-inflammatory and anti-viral properties in various studies.

Is 4-Amino-5-fluoro-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone (CAS: 145986-26-1) safe?

4-Amino-5-fluoro-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone is generally safe when handled according to proper safety guidelines. However, it is important to follow safety precautions such as wearing appropriate personal protective equipment (PPE) and ensuring good ventilation during the handling of the compound. Storage should be in a secure location away from ignition sources.

How should 4-Amino-5-fluoro-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone (CAS: 145986-26-1) be stored?

4-Amino-5-fluoro-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent degradation. The compound should be stored at a temperature not exceeding 25°C to ensure stability and minimize the risk of reaction or decomposition.

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