3-Amino-3-phenyl-1-propanol

Basic Information

View in Editor

CAS Number

14593-04-5

Molecular Formula

C9H13NO

Molecular Weight

151.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Physical State

Powder

Melting Point

73.0 to 77.0 deg-C

Boiling Point

134°C/4mmHg

Flash Point

293 °C at 760 mmHg

Refractive Index

1.4755 (estimate)

SMILES

View in Editor

C1=CC=C(C=C1)C(CCO)N

InChI

InChI=1S/C9H13NO/c10-9(6-7-11)8-4-2-1-3-5-8/h1-5,9,11H,6-7,10H2

InChIKey

SEQXIQNPMQTBGN-UHFFFAOYSA-N

LogP

1.0688

Topological Polar Surface Area

46.25 Å²

Hydrogen Bond Donor/Acceptor

3 / 2

Complexity

99.7

Safety Information

View Safety Information

GHS Hazard Pictograms

H314

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Synonyms & References

English

CS-W002696
3-phenyl-dl-beta-alaninol
BENZENEPROPANOL, GAMMA-AMINO-
3-amino-3-phenylpropan-1-ol
DL-ss-Phenylalaninol
S-beta-Phe-ol
BRN 0509667
1-Propanol, 3-amino-3-phenyl;3-PHENYL-DL-BETA-ALANINOL
(S)-3-Amino-3-phenyl-1-propanol
HEXAKETOCYCLOHEXANEOCTAHYDRATE97
SY033781
(3S)-3-amino-3-phenylpropan-1-ol; (s)-1-phenyl-3-propanolamine; (s)-3-phenyl-beta-alaninol
FT-0630325
SCHEMBL906234
AS-18893
EN300-39414
R-3-amino-3-phenylpropan-1-ol
SY013381
14593-04-5
SB44742
AKOS005146495
SY002040
3-Amino-3-phenyl-propan-1-ol
4-13-00-01919 (Beilstein Handbook Reference)
AB07310
SB44182
3-Amino-3-phenyl-1-propanol, AldrichCPR
SEQXIQNPMQTBGN-UHFFFAOYSA-N
3-amino-3-phenylpropanol
Z382816560
FT-0630323

MDL Number

MFCD00801124

Customs Code

2922199090

FAQ

What are the physical and chemical properties of 3-Amino-3-phenyl-1-propanol (CAS: 14593-04-5)?

3-Amino-3-phenyl-1-propanol (CAS: 14593-04-5) is a colorless to light yellow liquid with a molecular weight of approximately 189.23 g/mol. It is slightly soluble in water and more soluble in organic solvents. This compound is known for its reactivity, particularly towards nucleophilic substitution reactions and condensation with aldehydes and ketones.

How is 3-Amino-3-phenyl-1-propanol (CAS: 14593-04-5) typically synthesized?

3-Amino-3-phenyl-1-propanol can be synthesized through the reduction of 3-oxo-3-phenyl-1-propanamine using hydrogen gas in the presence of a palladium catalyst, such as Pd/C. The reaction requires a suitable solvent like ethanol and is carried out under controlled conditions to achieve high selectivity and yield.

What industries use 3-Amino-3-phenyl-1-propanol (CAS: 14593-04-5)?

3-Amino-3-phenyl-1-propanol (CAS: 14593-04-5) is commonly used in the pharmaceutical industry for the synthesis of drugs, particularly those requiring amino functionality. It also finds applications in the polymer industry for the modification of materials, and in sensor and semiconductor technologies for its unique reactivity.

What precautions should be taken when handling 3-Amino-3-phenyl-1-propanol (CAS: 14593-04-5)?

When handling 3-Amino-3-phenyl-1-propanol (CAS: 14593-04-5), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. This compound should be stored in a cool, dry place and away from direct sunlight. Handling should be done in a fume hood to minimize exposure. In case of spills, immediate cleanup is necessary, and the Material Safety Data Sheet (MSDS) should be consulted for proper disposal procedures.