Tegaserod | CAS No. 145158-71-0

Tegaserod

Basic Information

View in Editor

CAS Number

145158-71-0

Molecular Formula

C16H23N5O

Molecular Weight

301.39 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

155°

Boiling Point

470.556°C at 760 mmHg

Density

1.18

SMILES

View in Editor

CCCCCN=C(N)NN=CC1=CNC2=C1C=C(C=C2)OC

InChI

InChI=1S/C16H23N5O/c1-3-4-5-8-18-16(17)21-20-11-12-10-19-15-7-6-13(22-2)9-14(12)15/h6-7,9-11,19H,3-5,8H2,1-2H3,(H3,17,18,21)

InChIKey

IKBKZGMPCYNSLU-UHFFFAOYSA-N

LogP

2.8145700000000007

Topological Polar Surface Area

85.29 Å²

Hydrogen Bond Donor/Acceptor

4 / 6

Complexity

385

Synonyms & References

English

TEGASEROD [EMA EPAR]
BRD-K88743730-001-01-0
HTF 919
Tegaserod (USAN/INN)
TEGASEROD [USAN]
SCHEMBL8194377
Hydrazinecarboximidamide, 2-((5-methoxy-1H-indol-3-yl)methylene)-N-pentyl-
AC-4564
NCGC00095192-03
BDBM79022
LS-14526
CHEBI:94540
cid_6918369
CHEMBL76370
(Z)-but-2-enedioic acid;1-[[(Z)-(5-methoxyindol-3-ylidene)methyl]amino]-2-pentylguanidine
2-[(5-methoxy-2,3-dihydro-1H-indol-3-yl)methylene]-N-pentylhydrazinecarboximidamide
EN300-117255
BSPBio_003270
D06056
A909403
HTF919
Zelnorm
UNII-458VC51857
NCGC00095192-05
2-amyl-1-[[(Z)-(5-methoxyindol-3-ylidene)methyl]amino]guanidine;maleic acid
1-[(E)-(5-methoxy-1H-indol-3-yl)methylideneamino]-2-pentylguanidine
Tegaserod
DTXCID4025955
(2E)-2-[(5-methoxy-1H-indol-3-yl)methylene]-N-pentylhydrazinecarboximidamide
TEGASEROD [VANDF]
CAS-145158-71-0

MDL Number

MFCD06660144

Customs Code

2933990090

FAQ

What is Tegaserod (CAS: 145158-71-0)?

Tegaserod is an iminoketone derivative that acts as a 5-HT4 receptor agonist. It is primarily used for the treatment of irritable bowel syndrome with constipation (IBS-C).

What are the main uses of Tegaserod (CAS: 145158-71-0)?

Tegaserod is mainly used for the treatment of irritable bowel syndrome with constipation (IBS-C). It has also been investigated for other gastrointestinal disorders but was withdrawn from the market due to cardiovascular safety concerns.

Is Tegaserod (CAS: 145158-71-0) safe?

Tegaserod has been associated with cardiovascular safety concerns and was withdrawn from the market. It is generally not considered safe for use. Always consult a healthcare provider before using this compound.

How should Tegaserod (CAS: 145158-71-0) be stored?

Tegaserod should be stored in a cool, dry place, away from direct sunlight and sources of heat. It should be kept in a tightly closed container to protect from moisture and light exposure. Store at room temperature (15-30°C) and avoid freezing.