4,7-Diazaspiro[2.5]octane dihydrochloride

Basic Information

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CAS Number

145122-56-1

Molecular Formula

C6H14Cl2N2

Molecular Weight

185.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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Cl.Cl.C1CC12CNCCN2

InChI

InChI=1S/C6H12N2.2ClH/c1-2-6(1)5-7-3-4-8-6;;/h7-8H,1-5H2;2*1H

InChIKey

MWCKCAQLDIGIMK-UHFFFAOYSA-N

LogP

0.5553999999999996

Topological Polar Surface Area

24.06 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

96.7

Synonyms & References

English

4,7-Diaza-spiro[2.5]octane dihydrochloride
4,7-Diazaspiro[2.5]octane dihydrochloride
4,7-DIAZASPIRO[2.5]OCTANE 2HCL
4,7-diazaspiro<2,5>octane dihydrochloride
4,7-Diazaspiro[2.5]octane, hydrochloride (1:2)
BCP09976
CHM0068708
AX8212227
AB0052617
Z4167
ST24023076
4,7-Diazaspiro[2.5]octane--hydrogen chloride (1/2)
4,7-diazaspiro[2.5]octane dihydrochloride

MDL Number

MFCD11506235

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 4,7-Diazaspiro[2.5]octane dihydrochloride (CAS: 145122-56-1)?

4,7-Diazaspiro[2.5]octane dihydrochloride is a colorless to white crystalline solid. It has a molecular weight of approximately 227.79 g/mol and is soluble in common organic solvents. The compound is mildly basic and can react with acidic compounds. It is insoluble in water but soluble in methanol, ethanol, and dichloromethane. It is stable under normal conditions but should be stored away from strong acids.

How is 4,7-Diazaspiro[2.5]octane dihydrochloride (CAS: 145122-56-1) typically synthesized?

4,7-Diazaspiro[2.5]octane dihydrochloride is typically synthesized by the condensation of 4-aminocyclohexanol and 1,7-octanedione, followed by the addition of HCl to form the dihydrochloride salt. The reaction is catalyzed by a suitable acid and proceeds with good yield and selectivity. This method allows for the production of the compound in a controlled and reproducible manner.

What industries use 4,7-Diazaspiro[2.5]octane dihydrochloride (CAS: 145122-56-1)?

4,7-Diazaspiro[2.5]octane dihydrochloride finds applications in the pharmaceutical industry as a precursor for the synthesis of certain drugs. It is also used in the polymer industry for the preparation of functionalized polymers. Additionally, it is utilized in the sensor industry for its specific reactivity and in semiconductor applications due to its unique structural properties.

What precautions should be taken when handling 4,7-Diazaspiro[2.5]octane dihydrochloride (CAS: 145122-56-1)?

When handling 4,7-Diazaspiro[2.5]octane dihydrochloride, it is crucial to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. The compound should be stored in a cool, dry place away from strong acids and bases. If a spill occurs, it should be cleaned up with caution, using appropriate methods as outlined in the safety data sheet (SDS). Working in a well-ventilated area or fume hood is recommended to prevent inhalation of the compound.