Desmethyl Telmisartan | CAS No. 144701-81-5

Desmethyl Telmisartan

Basic Information

CAS Number

144701-81-5

Molecular Formula

C32H28N4O2

Molecular Weight

500.6 g/mol

AD

Basic Physical Properties

CCCC1=NC2=C(N1CC3=CC=C(C=C3)C4=CC=CC=C4C(=O)O)C=C(C=C2C)C5=NC6=CC=CC=C6N5

InChI

InChI=1S/C32H28N4O2/c1-3-8-29-35-30-20(2)17-23(31-33-26-11-6-7-12-27(26)34-31)18-28(30)36(29)19-21-13-15-22(16-14-21)24-9-4-5-10-25(24)32(37)38/h4-7,9-18H,3,8,19H2,1-2H3,(H,33,34)(H,37,38)

InChIKey

VRBXIPRPTFMJQC-UHFFFAOYSA-N

LogP

7.254020000000006

Topological Polar Surface Area

83.8 Ų

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

800

Synonyms & References

English

  • N-Desmethyl Telmisartan
  • [1,1'-Biphenyl]-2-carboxylic acid, 4'-[(4'-methyl-2'-propyl[2, 6'-bi-1H-benzimidazol]-1'-yl) methyl]-
  • DESMETHYL TELMISARTAN
  • NSC23766
  • 4'-((7'-methyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid
  • [1,1'-Biphenyl]-2-carboxylic acid, 4'-[(4'-methyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-
  • A1-01720
  • Desmethyl Telmisartan
  • 2-[4-[[6-(1H-benzimidazol-2-yl)-4-methyl-2-propylbenzimidazol-1-yl]methyl]phenyl]benzoic acid
  • Telmisartan N-Desmethyl Impurity
  • Z6WF679M7V
  • 4'-((7'-Methyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid
  • 144701-81-5
  • VRBXIPRPTFMJQC-UHFFFAOYSA-N
  • DTXSID00579024
  • 4'-[(4'-Methyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl][1,1'-biphenyl]-2-carboxylic Acid
  • SCHEMBL7299069
  • 4'-{[6-(1H-1,3-benzodiazol-2-yl)-4-methyl-2-propyl-1H-1,3-benzodiazol-1-yl]methyl}-[1,1'-biphenyl]-2-carboxylic acid
  • 4'-[(7'-Methyl-2'-propyl[1H,3'H-[2,5'-bibenzimidazole]]-3'-yl)methyl][1,1'-biphenyl]-2-carboxylic acid
  • 4'-[[2-n-Propyl-4-methyl-6-(benzimidazol-2-yl)-benzimidazol-1-yl]-methyl]-biphenyl-2-carboxylic acid

MDL Number

MFCD21363864

FAQ

What regulatory guidelines apply to Desmethyl Telmisartan (CAS: 144701-81-5)?

Desmethyl Telmisartan (CAS: 144701-81-5) is regulated under various guidelines, including GHS classification for hazardous substances, REACH regulations for registration, evaluation, authorization, and restriction of chemicals, and FDA and EPA requirements for drug substances and environmental protection, respectively.

Are there alternatives to Desmethyl Telmisartan (CAS: 144701-81-5) in synthesis?

Yes, there are alternatives to Desmethyl Telmisartan (CAS: 144701-81-5) in synthesis, such as using isomers or analogs like Desmethyl Olmesartan, which can serve similar therapeutic purposes but with potentially different metabolic profiles and reactivity.

What is the market or research trend for Desmethyl Telmisartan (CAS: 144701-81-5)?

The market trend for Desmethyl Telmisartan (CAS: 144701-81-5) reflects a focus on hypertension treatment, with ongoing research into its efficacy and safety, particularly in combination therapies. The trend also shows increasing interest in understanding its pharmacokinetics and pharmacodynamics.

How should waste containing Desmethyl Telmisartan (CAS: 144701-81-5) be handled?

Waste containing Desmethyl Telmisartan (CAS: 144701-81-5) should be collected in appropriate containers, labeled with the chemical name and CAS number. It should be disposed of through incineration or professional waste disposal services, following local and national environmental protection regulations to ensure safety and compliance.

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