1-Methyl-4-piperidinone

Basic Information

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CAS Number

1445-73-4

Molecular Formula

C6H11NO

Molecular Weight

113.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

72°C/17mmHg

Water Solubility

MISCIBLE

Refractive Index

1.46-1.462

SMILES

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CN1CCC(=O)CC1

InChI

InChI=1S/C6H11NO/c1-7-4-2-6(8)3-5-7/h2-5H2,1H3

InChIKey

HUUPVABNAQUEJW-UHFFFAOYSA-N

LogP

0.2811000000000001

Topological Polar Surface Area

20.310000000000002 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

90.7

Safety Information

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GHS Hazard Pictograms

H226

Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

Hazard Class

Class 3 Class 3

Sensitiveness

Air Sensitive

Synonyms & References

English

W923NR2QCS
SCHEMBL6527362
1-methyl-piperidin-4-one
W-108155
EN300-19200
FT-0608068
N-Methyl-4-piperidone, 97%
N-Methyl-4-piperidinone
N-methylpiperidine-4-one
AKOS000118953
1-Methylpiperidine-4-one
4-PIPERIDINONE, 1-METHYL-
MFCD00006191
1-Methyl-4-oxopiperidine
NSC66491
AM20080337
1-Methyl-4-pyperidone
CS-W009198
F0001-0514
1-Methyl-4-piperidone
M0530
BCP23149
NSC-66491
NSC 66491
EINECS 215-895-5
N-methyl-4 -piperidone
STR00612
1-Methyl-4-piperidinone
BP-10595
1-Methyl4-piperidone
1-Methyl-4-piperidone, distilled from glass

MDL Number

MFCD00006191

Customs Code

2934999090

FAQ

What is 1-Methyl-4-piperidinone (CAS: 1445-73-4)?

1-Methyl-4-piperidinone is a cyclic ketone compound with the chemical formula C6H11NO. It features a six-membered piperidine ring with a ketone group at position 4 and a methyl substituent at position 1. This compound is commonly used as an intermediate in organic synthesis due to its reactivity and structural versatility. It is a colorless liquid with a characteristic odor and is soluble in polar solvents.

What are the main uses of 1-Methyl-4-piperidinone (CAS: 1445-73-4)?

1-Methyl-4-piperidinone is primarily utilized in pharmaceutical research for synthesizing antibiotics, antifungals, and other bioactive molecules. It also serves as an industrial chemical intermediate and is employed in the production of dyes, pesticides, and polymer materials. In research settings, it is valued for its role in creating complex organic structures and functionalized compounds.

Is 1-Methyl-4-piperidinone (CAS: 1445-73-4) safe?

1-Methyl-4-piperidinone is considered moderately hazardous and should be handled with care. It may cause skin and eye irritation, and prolonged exposure could lead to respiratory issues. Safety standards recommend using personal protective equipment (PPE) such as gloves and goggles, and working in a well-ventilated area. Proper disposal and adherence to OSHA guidelines are essential for safe handling.

How should 1-Methyl-4-piperidinone (CAS: 1445-73-4) be stored?

1-Methyl-4-piperidinone should be stored in a sealed, light-resistant container in a cool (below 25°C), dry, and well-ventilation area. It is stable under these conditions but should be kept away from heat, moisture, and incompatible substances like strong oxidizers. Storage lifespan is typically long-term when properly preserved, but regular checks for contamination or degradation are advised.