(2R)-2-(4-Fluorophenyl)-N-[4-(2-{[2-methoxy-4-(methylsulfonyl)phenyl]amino}[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl]propanamide | CAS No. 1443763-60-7

(2R)-2-(4-Fluorophenyl)-N-[4-(2-{[2-methoxy-4-(methylsulfonyl)phenyl]amino}[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl]propanamide

Basic Information

CAS Number

1443763-60-7

Molecular Formula

C29H26FN5O4S

Molecular Weight

559.62 g/mol

AD

Basic Physical Properties

C[C@H](c1ccc(cc1)F)C(=O)Nc2ccc(cc2)c3ccc4nc(nn4c3)Nc5ccc(cc5OC)S(=O)(=O)C

InChI

InChI=1S/C29H26FN5O4S/c1-18(19-4-9-22(30)10-5-19)28(36)31-23-11-6-20(7-12-23)21-8-15-27-33-29(34-35(27)17-21)32-25-14-13-24(40(3,37)38)16-26(25)39-2/h4-18H,1-3H3,(H,31,36)(H,32,34)/t18-/m1/s1

InChIKey

NRJKIOCCERLIDG-GOSISDBHSA-N

LogP

5.4333000000000045

Topological Polar Surface Area

114.69 Ų

Hydrogen Bond Donor/Acceptor

2 / 9

Complexity

951

Safety Information

View Safety Information

GHS Hazard Pictograms

H302H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

  • BAY 1161909
  • BAY-1161909
  • Empesertib
  • Mps1-IN-5
  • 02Y3Z2756M
  • (2R)-2-(4-fluorophenyl)-N-[4-[2-(2-methoxy-4-methylsulfonylanilino)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]phenyl]propanamide
  • (R)-2-(4-fluorophenyl)-N-(4-(2-((2-methoxy-4-(methylsulfonyl)phenyl)amino)-[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl)propanamide
  • Empesertib [INN]
  • Empesertib [WHO-DD]
  • GTPL9427
  • BDBM329334
  • BCP23811
  • BAY1161909;Mps1-IN-5
  • BAY1161909

MDL Number

MFCD28902188

FAQ

What is (2R)-2-(4-Fluorophenyl)-N-[4-(2-{[2-methoxy-4-(methylsulfonyl)phenyl]amino}[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl]propanamide (CAS: 1443763-60-7)?

(2R)-2-(4-Fluorophenyl)-N-[4-(2-{[2-methoxy-4-(methylsulfonyl)phenyl]amino}[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl]propanamide is a complex organic compound with the CAS number 1443763-60-7. It is a derivative of a substituted triazolopyridine with a fluorophenyl group and a propylamine side chain. This compound is used in research for its potential biological activities.

What are the main uses of (2R)-2-(4-Fluorophenyl)-N-[4-(2-{[2-methoxy-4-(methylsulfonyl)phenyl]amino}[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl]propanamide (CAS: 1443763-60-7)?

(2R)-2-(4-Fluorophenyl)-N-[4-(2-{[2-methoxy-4-(methylsulfonyl)phenyl]amino}[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl]propanamide is primarily used in pharmaceutical research due to its potential biological activities. It may also be used for developing new drug candidates and as a tool compound in biological assays.

Is (2R)-2-(4-Fluorophenyl)-N-[4-(2-{[2-methoxy-4-(methylsulfonyl)phenyl]amino}[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl]propanamide (CAS: 1443763-60-7) safe?

(2R)-2-(4-Fluorophenyl)-N-[4-(2-{[2-methoxy-4-(methylsulfonyl)phenyl]amino}[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl]propanamide is generally safe when handled appropriately. However, it is important to follow all safety guidelines, including the use of appropriate personal protective equipment (PPE) and proper storage conditions to minimize exposure and risks.

How should (2R)-2-(4-Fluorophenyl)-N-[4-(2-{[2-methoxy-4-(methylsulfonyl)phenyl]amino}[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl]propanamide (CAS: 1443763-60-7) be stored?

(2R)-2-(4-Fluorophenyl)-N-[4-(2-{[2-methoxy-4-(methylsulfonyl)phenyl]amino}[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl]propanamide should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent moisture and light exposure. Handle with care to avoid skin contact and inhalation, following all safety guidelines and PPE recommendations.

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