Axitinib Impurity 4

Basic Information

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CAS Number

1443118-73-7

Molecular Formula

C22H20N4OS

Molecular Weight

388.5 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

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CNC(=O)c1ccccc1Sc2ccc3c(c2)[nH]nc3CCc4ccccn4

InChI

InChI=1S/C22H20N4OS/c1-23-22(27)18-7-2-3-8-21(18)28-16-10-11-17-19(25-26-20(17)14-16)12-9-15-6-4-5-13-24-15/h2-8,10-11,13-14H,9,12H2,1H3,(H,23,27)(H,25,26)

InChIKey

JPTQVDRPKXSDDN-UHFFFAOYSA-N

LogP

4.2539000000000025

Topological Polar Surface Area

70.67 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Synonyms & References

English

Dihydro-Axitinib
N-methyl-2-((3-(2-(pyridin-2-yl)ethyl)-1H-indazol-6-yl)thio)benzamide

FAQ

What regulatory guidelines apply to Axitinib Impurity 4 (CAS: 1443118-73-7)?

Axitinib Impurity 4 (CAS: 1443118-73-7) falls under various regulatory guidelines including GHS classification, REACH regulations, and FDA/EPA related requirements. It is important to adhere to these guidelines for safe handling and disposal. Additionally, specific national and regional regulations may apply, so it is essential to consult the latest regulatory documents for compliance.

Are there alternatives to Axitinib Impurity 4 (CAS: 1443118-73-7) in synthesis?

While Axitinib Impurity 4 (CAS: 1443118-73-7) is a specific compound, there are alternative impurities and reagents that can be used in synthesis processes. For example, using other axitinib impurities or different starting materials can provide alternative routes. However, the choice of alternative reagents should be guided by the specific requirements of the synthesis and regulatory compliance.

What is the market or research trend for Axitinib Impurity 4 (CAS: 1443118-73-7)?

The market for Axitinib Impurity 4 (CAS: 1443118-73-7) is closely tied to the broader market for axitinib, a tyrosine kinase inhibitor. Research trends indicate a focus on pharmaceuticals and oncology applications. Market trends show increasing demand for purity and quality control in pharmaceutical intermediates, driving the need for research and development in impurity analysis and removal techniques.

How should waste containing Axitinib Impurity 4 (CAS: 1443118-73-7) be handled?

Waste containing Axitinib Impurity 4 (CAS: 1443118-73-7) should be collected in appropriate containers and disposed of according to local regulations. Proper incineration or professional waste disposal services are recommended to ensure environmental safety. It is crucial to follow safety protocols to avoid exposure and to minimize environmental impact during the disposal process.