4,4-Difluoropiperidine hydrochloride (1:1)

Basic Information

View in Editor

CAS Number

144230-52-4

Molecular Formula

C5H10ClF2N

Molecular Weight

157.59 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

173-177 °C

Boiling Point

114.3 °C at 760 mmHg

Density

1.222

Flash Point

22.9 °C

Refractive Index

1.472

SMILES

View in Editor

Cl.FC1(F)CCNCC1

InChI

InChI=1S/C5H9F2N.ClH/c6-5(7)1-3-8-4-2-5;/h8H,1-4H2;1H

InChIKey

OABUKBBBSMNNPM-UHFFFAOYSA-N

LogP

1.4269

Topological Polar Surface Area

12.03 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

74.5

Safety Information

View Safety Information

GHS Hazard Pictograms

H319

Hazard Statement

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Sensitiveness

Hygroscopic

Synonyms & References

English

4,4-Difluoropiperidine hydrochloride
4,4-DifluoropiperidineHCl
4,4-Difluoropiperidine hy...
Piperidine, 4,4-difluoro-, hydrochloride (1:1)
Piperidine,4,4-difluoro-, hydrochloride (9CI)
4,4-DIFLUOROPIPERIDINE HCL
Piperidine, 4,4-difluoro-, hydrochloride
4,4-difluoropiperidine, chloride
4,4-Difluoropiperidinehydrochloride
PubChem6797
4,4-difluoropiperidin HCl
4,4-difluoropiperidine-hcl
4,4-Difluoropiperidine, HCl
difluoropiperidine hydrochloride
4,4-difluoropiperidine-HCl salt
4,4-difluoropiperidine HCl salt
4,4-difluoropiperidine hydrochloride
4,4-Difluoro-piperidine hydrochloride

MDL Number

MFCD03095381

Customs Code

2933399090

FAQ

What regulatory guidelines apply to 4,4-Difluoropiperidine hydrochloride (CAS: 144230-52-4)?

4,4-Difluoropiperidine hydrochloride (CAS: 144230-52-4) is subject to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) for classification and labelling. In the European Union, it must comply with REACH regulations. For FDA and EPA requirements, it falls under the specific provisions for pharmaceutical and chemical substances. It is important to consult the latest regulatory documents for specific guidelines and safety data sheets (SDS) for detailed information.

Are there alternatives to 4,4-Difluoropiperidine hydrochloride (CAS: 144230-52-4) in synthesis?

There are several alternatives to 4,4-Difluoropiperidine hydrochloride (CAS: 144230-52-4) that can be used in synthesis, such as other piperidine derivatives or fluorinated analogs. Common alternatives include 4-fluoropiperidine and 4-methylpiperidine. These can offer similar functionalities and properties, but the choice depends on the specific experimental conditions and desired outcomes.

What is the market or research trend for 4,4-Difluoropiperidine hydrochloride (CAS: 144230-52-4)?

The market for 4,4-Difluoropiperidine hydrochloride (CAS: 144230-52-4) is growing due to its applications in pharmaceuticals and organic synthesis. Research trends indicate increasing interest in its use as a precursor for the synthesis of various bioactive compounds. Price trends show fluctuations based on supply and demand, with a growing emphasis on sustainable and environmentally friendly production methods.

How should waste containing 4,4-Difluoropiperidine hydrochloride (CAS: 144230-52-4) be handled?

Waste containing 4,4-Difluoropiperidine hydrochloride (CAS: 144230-52-4) should be collected in appropriate containers and stored in a well-ventilated area. It is essential to follow local waste disposal regulations, which may require professional incineration or other specialized disposal methods. Environmental protection measures include proper containment to prevent spillage and ensure that waste is treated according to hazardous waste guidelines to minimize environmental impact.