Eprosartan mesylate

Basic Information

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CAS Number

144143-96-4

Molecular Formula

C24H28N2O7S2

Molecular Weight

520.6 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

246.0 to 250.0 deg-C

Boiling Point

660.6°C at 760 mmHg

Density

1.26

Flash Point

353.3 ºC

Solubility

DMSO: >10mg/mL

SMILES

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CCCCC1=NC=C(N1CC2=CC=C(C=C2)C(=O)O)C=C(CC3=CC=CS3)C(=O)O.CS(=O)(=O)O

InChI

InChI=1S/C23H24N2O4S.CH4O3S/c1-2-3-6-21-24-14-19(12-18(23(28)29)13-20-5-4-11-30-20)25(21)15-16-7-9-17(10-8-16)22(26)27;1-5(2,3)4/h4-5,7-12,14H,2-3,6,13,15H2,1H3,(H,26,27)(H,28,29);1H3,(H,2,3,4)/b18-12+;

InChIKey

DJSLTDBPKHORNY-XMMWENQYSA-N

LogP

4.248400000000002

Topological Polar Surface Area

146.79 Å²

Hydrogen Bond Donor/Acceptor

3 / 9

Complexity

711

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

SK&F-108566-J
EPROSARTAN MESYLATE (USP-RS)
SK&F 108566-J
Tox21_112186_1
EPROSARTAN MESYLATE [VANDF]
CHEBI:48409
(E)-alpha-((2-butyl-1-((4-carboxyphenyl)methyl)-1H-imidazol-5-yl)methylene)-2-thiophenepropanoic acid monomethanesulfonate
Eprosartanmesylate
(E)-4-((2-Butyl-5-(2-carboxy-3-(thiophen-2-yl)prop-1-en-1-yl)-1H-imidazol-1-yl)methyl)benzoic acid methanesulfonic acid salt
(E)-2-BUTYL-1-(P-CARBOXYBENZYL)-.ALPHA.-2-THENYLIMIDAZOLE-5-ACRYLIC ACID, MONOMETHANESULFONATE
EPROSARTAN MONOMETHANESULFONATE [MI]
DTXCID5024217
EPROSARTAN MESYLATE [USP MONOGRAPH]
SKF-108566J
SR-05000001450-2
EPROSARTAN MESILATE [MART.]
Eprosartan mesylate, United States Pharmacopeia (USP) Reference Standard
AM84399
AKOS015994738
EPROSARTAN MESYLATE [ORANGE BOOK]
eprosartan methanesulfonate
HMS3885B05
(E)-2-Butyl-1-(p-carboxybenzyl)-alpha-2-thenylimidazole-5-acrylic acid, monomethanesulfonate
SK&F 108566
Teveten (TN)
Regulaten
HMS3262B17
EPROSARTAN MESYLATE COMPONENT OF TEVETEN HCT
Epro-sartan mesylate dihydrate
TEVETEN HCT COMPONENT EPROSARTAN MESYLATE
2-THIOPHENEPROPANOIC ACID, alpha-((2-BUTYL-1-((4-CARBOXYPHENYL)METHYL)-1H-IMIDAZOL-5-YL)METHYLENE)-, (E)-, MONOMETHANESULPHONATE

MDL Number

MFCD08141807

Customs Code

2934999090

FAQ

What is Eprosartan mesylate (CAS: 144143-96-4)?

Eprosartan mesylate is an angiotensin II receptor antagonist used in the treatment of hypertension and diabetic nephropathy. It is a white to off-white crystalline powder with a molecular formula of C27H31N3O7·CH4SO3 and a molecular weight of 547.62.

What are the main uses of Eprosartan mesylate (CAS: 144143-96-4)?

Eprosartan mesylate is primarily used in the treatment of hypertension and diabetic nephropathy. It is also used in managing proteinuria in patients with diabetic nephropathy and hypertension. Its main applications include oral administration to patients with these conditions.

Is Eprosartan mesylate (CAS: 144143-96-4) safe?

Eprosartan mesylate is generally safe when used as directed. However, like any medication, it can have side effects. Common side effects include dizziness, fatigue, and hyperkalemia. Precautions include monitoring blood potassium levels and ensuring there are no contraindications with other medications. Always follow a healthcare provider’s instructions.

How should Eprosartan mesylate (CAS: 144143-96-4) be stored?

Eprosartan mesylate should be stored at room temperature (15-30°C or 59-86°F) in a tightly closed container to protect it from light and moisture. It should be kept out of reach of children and pets. Storing it in a cool, dry place can help maintain its efficacy and stability.