(3S)-N,N-Dimethyl-3-pyrrolidinamine dihydrochloride

Basic Information

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CAS Number

144043-20-9

Molecular Formula

C6H16Cl2N2

Molecular Weight

187.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Solid

Melting Point

176-181°C

Specific Rotation

-3.70° (c=1, water)

SMILES

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CN(C)C1CCNC1.Cl.Cl

InChI

InChI=1S/C6H14N2.2ClH/c1-8(2)6-3-4-7-5-6;;/h6-7H,3-5H2,1-2H3;2*1H/t6-;;/m0../s1

InChIKey

LCPKWRSLMCUOOZ-ILKKLZGPSA-N

LogP

0.7534999999999998

Topological Polar Surface Area

15.27 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

70.9

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

Hygroscopic

Synonyms & References

English

(3S)-N,N-Dimethylpyrrolidin-3-amine--hydrogen chloride (1/2)
(S)-N,N-dimethylpyrrolidin-3-amine dihydrochloride
SCHEMBL18424739
(S)-3-(Dimethylamino)pyrrolidine 2HCl
AM803215
BCP10040
3-Pyrrolidinamine, N,N-dimethyl-, hydrochloride (1:2), (3S)-
DTXSID60703863
MFCD08561117
EN300-6748369
(3S)-N,N-dimethylpyrrolidin-3-amine dihydrochloride
(S)-3-DIMETHYLAMINOPYRROLIDINEDIHYDROCHLORIDE
(3S)-N,N-dimethylpyrrolidin-3-amine;dihydrochloride
(3s)-3-(dimethylamino)pyrrolidine dihydrochloride
(S)-(-)-3-Dimethylaminopyrrolidine dihydrochloride
3-Pyrrolidinamine,N,N-dimethyl-,hydrochloride(1:2),(3S)-
(S)-3-DIMETHYLAMINOPYRROLIDINE DIHYDROCHLORIDE
144043-20-9
(S)-(+)-N,N-Dimethyl-3-pyrrolidinamine dihydrochloride
AS-18111
(S)-3-Dimethylaminopyrrolidine 2HCl
AKOS015844957
(3S)-(-)-3-(Dimethylamino)pyrrolidine dihydrochloride
(S)-3-Dimethylaminopyrrolidine dihydrochloride
3-Pyrrolidinamine,N,N-dimethyl-, hydrochloride (1:2), (3S)-
(3S)-N,N-dimethylpyrrolidin-3-amine,dihydrochloride
(S)-(-)-3-Dimethylaminopyrroli
(3S)-N,N-Dimethylpyrrolidin-3-amine hydrochloride
KS

MDL Number

MFCD08561117

Customs Code

2933990090

FAQ

What are the physical and chemical properties of (3S)-N,N-Dimethyl-3-pyrrolidinamine dihydrochloride (CAS: 144043-20-9)?

(3S)-N,N-Dimethyl-3-pyrrolidinamine dihydrochloride is a white crystalline solid with a molecular weight of approximately 239.68 g/mol. It is soluble in water and has a slightly acidic nature due to the presence of the dihydrochloride moiety. The compound is stable under normal conditions but should be stored away from moisture and heat to prevent hydrolysis. It exhibits moderate reactivity in basic conditions.

How is (3S)-N,N-Dimethyl-3-pyrrolidinamine dihydrochloride (CAS: 144043-20-9) typically synthesized?

(3S)-N,N-Dimethyl-3-pyrrolidinamine dihydrochloride can be synthesized by the reaction of 3-pyrrolidinamine with hydrochloric acid. Commonly, the 3-pyrrolidinamine is dissolved in an appropriate solvent, and hydrochloric acid is added under controlled conditions to form the dihydrochloride salt. The reaction is typically carried out under mild conditions to maintain the purity of the product.

What industries use (3S)-N,N-Dimethyl-3-pyrrolidinamine dihydrochloride (CAS: 144043-20-9)?

(3S)-N,N-Dimethyl-3-pyrrolidinamine dihydrochloride is used in the pharmaceutical industry for the synthesis of certain drugs, particularly those requiring chiral centers. It is also utilized in the polymer industry for the production of biocompatible polymers and in the sensor industry for its ability to bind to specific analytes. Additionally, it finds applications in the semiconductor industry as a precursor in the manufacturing of electronic materials.

What precautions should be taken when handling (3S)-N,N-Dimethyl-3-pyrrolidinamine dihydrochloride (CAS: 144043-20-9)?

When handling (3S)-N,N-Dimethyl-3-pyrrolidinamine dihydrochloride, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be stored in a well-ventilated area away from moisture and heat. Fume hoods should be used during manipulation to prevent inhalation of the compound or its vapor. In case of a spill, it should be cleaned up promptly using appropriate absorbent materials, and the area should be thoroughly washed down. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal procedures.