Sodium [(4-aminophenyl)sulfonyl](1,3-thiazol-2-yl)azanide

Basic Information

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CAS Number

144-74-1

Molecular Formula

C9H8N3NaO2S2

Molecular Weight

277.3 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

175 deg C (form a); 202 deg C (form b)

Boiling Point

479.5°C at 760 mmHg

Flash Point

243.8°C

Solubility

H2O: soluble50mg/mL

SMILES

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C1=CC(=CC=C1N)S(=O)(=O)[N-]C2=NC=CS2.[Na+]

InChI

InChI=1S/C9H8N3O2S2.Na/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9;/h1-6H,10H2;/q-1;+1

InChIKey

GWIJGCIVKLITQK-UHFFFAOYSA-N

LogP

3.04690

Complexity

326

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

sodium [(4-aminophenyl)sulfonyl](1,3-thiazol-2-yl)azanide
Sodium((4-aminophenyl)sulfonyl)(thiazol-2-yl)amide
HY-B0507A
NCGC00357116-01
Sulfathiazole sodium salt, >=99%
GWIJGCIVKLITQK-UHFFFAOYSA-N
Benzenesulfonamide, 4-amino-N-2-thiazolyl-, sodium salt (1:1)
SULFATHIAZOLE SODIUM [MART.]
Monosodium 2-sulfanilamidothiazole
UNII-PV16N742VM
BCP13309
SR-01000883699
Sulfanilamide, N(sup 1)-2-thiazolyl-, N(sup 1)-sodium deriv.
AI3-26815
sodium;(4-aminophenyl)sulonyl-(1,3-thiazol-2-yl)azanide
W-108149
Sodium sulfathiazole
MFCD00072133
sodium (4-aminophenylsulfonyl)(thiazol-2-yl)amide
Sodium, (N(sup 1)-2-thiazolylsulfanilamido)-
DTXCID2030279
AS-82169
CAS-144-74-1
Benzenesulfonamide, 4-amino-N-2-thiazolyl-, monosodium salt
4-Amino-N-(2-thiazolyl)benzenesulfonamide sodium salt
Sulfathiazole sodium salt
SULFATHIAZOLE SODIUM [WHO-DD]
NS00041827
AKOS032953796
N(sup 1)-2-Thiazolylsulfanilamide sodium salt
Sodium norsulfazole

MDL Number

MFCD12912680

Customs Code

2935009090

FAQ

What is Sodium [(4-aminophenyl)sulfonyl](1,3-thiazol-2-yl)azanide (CAS: 144-74-1)?

Sodium [(4-aminophenyl)sulfonyl](1,3-thiazol-2-yl)azanide (CAS: 144-74-1) is a sodium salt containing a 4-aminophenylsulfonyl group and a 1,3-thiazol-2-yl ring. Its chemical formula is C9H10N3O2S2Na, and it is a white crystalline solid with high solubility in polar solvents. This compound is notable for its stability and reactivity in organic synthesis, particularly in forming sulfonamide derivatives and heterocyclic compounds.

What are the main uses of Sodium [(4-aminophenyl)sulfonyl](1,3-thiazol-2-yl)azanide (CAS: 144-74-1)?

Sodium [(4-aminophenyl)sulfonyl](1,3-thiazol-2-yl)azanide (CAS: 144-74-1) is primarily used in pharmaceutical research as a key intermediate for drug development, especially in antifungal and antibiotic compounds. It also finds applications in organic synthesis for creating sulfonamide-based molecules. Additionally, it is utilized in industrial chemical processes and as a research reagent for studying heterocyclic chemistry and functional group modifications.

Is Sodium [(4-aminophenyl)sulfonyl](1,3-thiazol-2-yl)azanide (CAS: 144-74-1) safe?

Sodium [(4-aminophenyl)sulfonyl](1,3-thiazol-2-yl)azanide (CAS: 144-74-1) requires careful handling due to potential toxicity via inhalation or skin contact. It should be stored in a sealed container and used in well-ventilated areas. Safety standards recommend wearing protective gloves, goggles, and a lab coat. Always follow proper disposal protocols to ensure environmental and occupational safety.

How should Sodium [(4-aminophenyl)sulfonyl](1,3-thiazol-2-yl)azanide (CAS: 144-74-1) be stored?

Sodium [(4-aminophenyl)sulfonyl](1,3-thiazol-2-yl)azanide (CAS: 144-74-1) should be stored in a cool, dry place, away from light and moisture. Keep it in an airtight container to maintain stability. It is generally stable under normal conditions but may degrade if exposed to high humidity or temperature fluctuations. Always store in a ventilated area to prevent airborne exposure.