2-(6,11-Dihydro-5H-dibenzo[b,e]azepin-6-ylmethyl)-1H-isoindole-1,3(2H)-dione | CAS No. 143878-20-0

2-(6,11-Dihydro-5H-dibenzo[b,e]azepin-6-ylmethyl)-1H-isoindole-1,3(2H)-dione

Basic Information

CAS Number

143878-20-0

Molecular Formula

C23H18N2O2

Molecular Weight

354.41 g/mol

AD

Basic Physical Properties

C1C2=CC=CC=C2C(NC3=CC=CC=C31)CN4C(=O)C5=CC=CC=C5C4=O

InChI

InChI=1S/C23H18N2O2/c26-22-18-10-4-5-11-19(18)23(27)25(22)14-21-17-9-3-1-7-15(17)13-16-8-2-6-12-20(16)24-21/h1-12,21,24H,13-14H2

InChIKey

XXHUCKUXFLTXAG-UHFFFAOYSA-N

LogP

4.040200000000003

Topological Polar Surface Area

49.410000000000004 Ų

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

567

Synonyms & References

English

  • 6-(phthalimidomethyl)-6,11-dihydro-5H-dibenz-[b,e]azepine
  • SCHEMBL5364032
  • AMY18451
  • FT-0658361
  • 6-(Phthalimidomethyl)-6,11-dihydro-5H-dibenz[b,e]azepine
  • MFCD09839031
  • 2-({9-azatricyclo[9.4.0.0(3),?]pentadeca-1(11),3,5,7,12,14-hexaen-10-yl}methyl)-2,3-dihydro-1H-isoindole-1,3-dione
  • CS-0060594
  • Phthalimidomethyl)-6,11-dihydro-5H-dibenz-[b,e]azepine
  • 1H-Isoindole-1,3(2H)-dione, 2-[(6,11-dihydro-5H-dibenz[b,e]azepin-6-yl)methyl]-
  • BCP14330
  • A808122
  • 2-((6,11-Dihydro-5H-dibenzo[b,e]azepin-6-yl)methyl)isoindoline-1,3-dione
  • J-007879
  • 6-(Phthalimidomethyl)-6,11-dihydro-5H-dibenz-[b,e]azepine(PMDAP)
  • XXHUCKUXFLTXAG-UHFFFAOYSA-N
  • 2-[(6,11-Dihydro-5H-dibenzo[b,e]azepin-6-yl)methyl]-1H-isoindole-1,3(2H)-dione
  • NS00004177
  • W17678
  • 2-(6,11-dihydro-5H-benzo[c][1]benzazepin-6-ylmethyl)isoindole-1,3-dione
  • DTXSID20433210
  • 143878-20-0
  • AKOS015895809
  • AS-73650
  • 6-(PHTHALIMIDOMETHYL)-6,11-DIHYDRO-5H-DIBENZ-B,EAZEPINE
  • 6-(Phthalimidomethyl)-6,11-dihydro-5h-dibenz[b,e]azepine
  • 5H-Dibenz[b,e]azepine,1H-isoindole-1,3(2H)-dione deriv.

MDL Number

MFCD09839031

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2-(6,11-Dihydro-5H-dibenzo[b,e]azepin-6-ylmethyl)-1H-isoindole-1,3(2H)-dione (CAS: 143878-20-0)?

2-(6,11-Dihydro-5H-dibenzo[b,e]azepin-6-ylmethyl)-1H-isoindole-1,3(2H)-dione is a solid with a crystalline form. It has a molecular weight of approximately 506.44 g/mol and is sparingly soluble in water. Chemically, it is stable under normal conditions but reacts with strong acids and bases. It is used in pharmaceutical and industrial applications.

How is 2-(6,11-Dihydro-5H-dibenzo[b,e]azepin-6-ylmethyl)-1H-isoindole-1,3(2H)-dione (CAS: 143878-20-0) typically synthesized?

2-(6,11-Dihydro-5H-dibenzo[b,e]azepin-6-ylmethyl)-1H-isoindole-1,3(2H)-dione is typically synthesized through a multi-step reaction involving the condensation of 6,11-dihydro-5H-dibenzo[b,e]azepin-6-ylmethyl alcohol with indole-3-carboxaldehyde. The process requires careful control of temperature and stoichiometry to achieve high yield and selectivity.

What industries use 2-(6,11-Dihydro-5H-dibenzo[b,e]azepin-6-ylmethyl)-1H-isoindole-1,3(2H)-dione (CAS: 143878-20-0)?

2-(6,11-Dihydro-5H-dibenzo[b,e]azepin-6-ylmethyl)-1H-isoindole-1,3(2H)-dione is used in the pharmaceutical industry for the synthesis of drug candidates. It is also employed in the polymer industry for the production of advanced materials and in the sensor industry for the development of sensitive detection devices.

What precautions should be taken when handling 2-(6,11-Dihydro-5H-dibenzo[b,e]azepin-6-ylmethyl)-1H-isoindole-1,3(2H)-dione (CAS: 143878-20-0)?

When handling 2-(6,11-Dihydro-5H-dibenzo[b,e]azepin-6-ylmethyl)-1H-isoindole-1,3(2H)-dione, it is advisable to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up carefully, and the Material Safety Data Sheet (MSDS) should be consulted for proper handling procedures.

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