5,7-Dibromo-6-fluoro-2-methyl-3,4-dihydro-1(2H)-quinolinecarbaldehyde | CAS No. 143703-25-7

5,7-Dibromo-6-fluoro-2-methyl-3,4-dihydro-1(2H)-quinolinecarbaldehyde

Basic Information

CAS Number

143703-25-7

Molecular Formula

C11H10Br2FNO

Molecular Weight

351.01 g/mol

AD

Basic Physical Properties

Brc2cc1c(CCC(C)N1C=O)c(Br)c2F

InChI

InChI=1S/C11H10Br2FNO/c1-6-2-3-7-9(15(6)5-16)4-8(12)11(14)10(7)13/h4-6H,2-3H2,1H3

InChIKey

ZZLQPWXVZCPUGC-UHFFFAOYSA-N

LogP

3.648200000000002

Topological Polar Surface Area

20.310000000000002 Ų

Hydrogen Bond Donor/Acceptor

0 / 2

Synonyms & References

English

  • CE3F4
  • CE3F4 NEW
  • 5,7-Dibromo-6-fluoro-3,4-dihydro-2-methyl-1(2H)-quinolinecarboxaldehyde

MDL Number

MFCD30182244

FAQ

What are the physical and chemical properties of 5,7-Dibromo-6-fluoro-2-methyl-3,4-dihydro-1(2H)-quinolinecarbaldehyde (CAS: 143703-25-7)?

5,7-Dibromo-6-fluoro-2-methyl-3,4-dihydro-1(2H)-quinolinecarbaldehyde is a crystalline solid with a high melting point. Its molecular weight is approximately 347.04 g/mol. This compound is poorly soluble in water but soluble in organic solvents such as ethanol and acetone. It exhibits good reactivity towards nucleophiles and is known for its electrophilic aromatic substitution and aldehyde functional group reactivity.

How is 5,7-Dibromo-6-fluoro-2-methyl-3,4-dihydro-1(2H)-quinolinecarbaldehyde (CAS: 143703-25-7) typically synthesized?

5,7-Dibromo-6-fluoro-2-methyl-3,4-dihydro-1(2H)-quinolinecarbaldehyde can be synthesized via a multi-step process involving bromination and fluoro-substitution of a precursor compound. Typically, the reaction involves the use of bromine and fluorinating agents in the presence of a suitable solvent. The yield can be improved by optimizing reaction conditions and using protective groups to control selectivity.

What industries use 5,7-Dibromo-6-fluoro-2-methyl-3,4-dihydro-1(2H)-quinolinecarbaldehyde (CAS: 143703-25-7)?

5,7-Dibromo-6-fluoro-2-methyl-3,4-dihydro-1(2H)-quinolinecarbaldehyde finds applications in the pharmaceutical industry as a starting material for synthesizing drug candidates. It is also used in the chemical industry, particularly in the development of new materials and sensors due to its unique chemical properties and functional groups.

What precautions should be taken when handling 5,7-Dibromo-6-fluoro-2-methyl-3,4-dihydro-1(2H)-quinolinecarbaldehyde (CAS: 143703-25-7)?

When handling 5,7-Dibromo-6-fluoro-2-methyl-3,4-dihydro-1(2H)-quinolinecarbaldehyde, appropriate personal protective equipment (PPE) such as gloves, lab coat, and safety goggles should be worn. This compound should be used in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for detailed emergency response procedures and storage recommendations.

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