2-Chloro-3-methylthiophene

Basic Information

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CAS Number

14345-97-2

Molecular Formula

C5H5ClS

Molecular Weight

132.62 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

54°C/15mmHg

Refractive Index

n20/D 1.5400(lit.)

SMILES

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CC1=C(SC=C1)Cl

InChI

InChI=1S/C5H5ClS/c1-4-2-3-7-5(4)6/h2-3H,1H3

InChIKey

KQFADYXPELMVHE-UHFFFAOYSA-N

LogP

2.709920000000001

Topological Polar Surface Area

0.0 Å²

Hydrogen Bond Donor/Acceptor

0 / 0

Complexity

65.1

Safety Information

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GHS Hazard Pictograms

H226

H302

H318

Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H302 Harmful if swallowed
Acute toxicity, oral

H318 Causes serious eye damage
Serious eye damage/eye irritation

Hazard Class

Class 3 Class 3

Synonyms & References

English

DTXSID50162425
GEO-00732
C1801
Q-101195
AC-4903
2-chlor-3-methylthiophen
2-Chloro-3-methyl thiophene
AMY23212
2-Chloro-3-methylthiophene
SCHEMBL157623
NS00024662
EN300-122371
J-506333
PS-3268
Thiophene, 2-chloro-3-methyl-
BGW3VN9CJC
AKOS005254523
EINECS 238-296-0
MFCD00130083
KQFADYXPELMVHE-UHFFFAOYSA-N
F11210
2-Chloro-3-methylthiophene, 97%
FT-0637063
14345-97-2
CS-W013401
2-chloro-3-methylthiopene
2-Chloro-3-methylthiophen
2-chloro-3-methyl-thiophene
Celite 545
2C3MT
2-Chloro-3-methylthi

MDL Number

MFCD00130083

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 2-Chloro-3-methylthiophene (CAS: 14345-97-2)?

2-Chloro-3-methylthiophene (CAS: 14345-97-2) is a colorless to pale yellow liquid with a molecular weight of approximately 143.01 g/mol. It has a low solubility in water (0.02 g/100 mL at 25°C) but is soluble in organic solvents like acetone and ethanol. The compound is moderately reactive, particularly towards nucleophiles and reducing agents.

How is 2-Chloro-3-methylthiophene (CAS: 14345-97-2) typically synthesized?

2-Chloro-3-methylthiophene (CAS: 14345-97-2) can be synthesized by chlorination of 3-methylthiophene using thionyl chloride as the chlorinating agent. The reaction involves heating 3-methylthiophene in the presence of thionyl chloride to produce the target compound with good yield and selectivity.

What industries use 2-Chloro-3-methylthiophene (CAS: 14345-97-2)?

2-Chloro-3-methylthiophene (CAS: 14345-97-2) is used in the pharmaceutical industry for the synthesis of certain drugs, in the polymer industry for the production of advanced polymers, and in the semiconductor industry for the fabrication of electronic materials. It also finds application in the manufacturing of sensors and as a chemical intermediate.

What precautions should be taken when handling 2-Chloro-3-methylthiophene (CAS: 14345-97-2)?

When handling 2-Chloro-3-methylthiophene (CAS: 14345-97-2), appropriate personal protective equipment (PPE) should be worn, including gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up according to the Material Safety Data Sheet (MSDS/SDS) guidelines. Proper storage should be in a cool, dry place away from heat sources and incompatible materials.