2-Chloro-3-methylthiophene(CAS: 14345-97-2)

2-Chloro-3-methylthiophene (CAS: 14345-97-2) is a colorless to pale yellow liquid with a molecular weight of approximately 143.01 g/mol. It has a low solubility in water (0.02 g/100 mL at 25°C) but is soluble in organic solvents like acetone and ethanol. The compound is moderately reactive, particularly towards nucleophiles and reducing agents.

2-Chloro-3-methylthiophene (CAS: 14345-97-2) can be synthesized by chlorination of 3-methylthiophene using thionyl chloride as the chlorinating agent. The reaction involves heating 3-methylthiophene in the presence of thionyl chloride to produce the target compound with good yield and selectivity.

2-Chloro-3-methylthiophene (CAS: 14345-97-2) is used in the pharmaceutical industry for the synthesis of certain drugs, in the polymer industry for the production of advanced polymers, and in the semiconductor industry for the fabrication of electronic materials. It also finds application in the manufacturing of sensors and as a chemical intermediate.

When handling 2-Chloro-3-methylthiophene (CAS: 14345-97-2), appropriate personal protective equipment (PPE) should be worn, including gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up according to the Material Safety Data Sheet (MSDS/SDS) guidelines. Proper storage should be in a cool, dry place away from heat sources and incompatible materials.