17-Hydroxy-19-norpregna-4,9-diene-3,20-dione | CAS No. 14340-01-3

17-Hydroxy-19-norpregna-4,9-diene-3,20-dione

Basic Information

CAS Number

14340-01-3

Molecular Formula

C20H26O3

Molecular Weight

314.43 g/mol

AD

Basic Physical Properties

Melting Point

203-205 ºC

CC(=O)C1(CCC2C1(CCC3=C4CCC(=O)C=C4CCC23)C)O

InChI

InChI=1S/C20H26O3/c1-12(21)20(23)10-8-18-17-5-3-13-11-14(22)4-6-15(13)16(17)7-9-19(18,20)2/h11,17-18,23H,3-10H2,1-2H3/t17-,18+,19+,20+/m1/s1

InChIKey

CRODSNSLNRWYAX-FYQPLNBISA-N

LogP

3.5125000000000024

Topological Polar Surface Area

54.370000000000005 Ų

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

656

Synonyms & References

English

  • AKOS025401803
  • (8S,13S,14S,17R)-17-acetyl-17-hydroxy-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
  • 14340-01-3
  • SCHEMBL544872
  • A905140
  • AC-25768
  • 19-Norpregna-4,9-diene-3,20-dione,17-hydroxy-
  • GESTADENE
  • Gestadienol
  • 17-hydroxy-19-nor-4-pregnene-3,20-dione
  • 17-Hydroxy-19-nor-pregn-4-en-3,20-dion
  • 17-hydroxy-19-norpregn-4-ene-3,20-dione
  • 17-hydroxy-19-norpregna-4,9-diene-3,20-dione
  • (8S,13S,14S,17R)-17-acetyl-17-hydroxy-13-methyl-1,2,6,7,8,11,12,1 4,15,16-decahydrocyclopenta[a]phenanthren-3-one
  • (8S,13S,14S,17R)-17-acetyl-17-hydroxy-13-methyl-1,2,6,7,8,11,12
  • 13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

MDL Number

MFCD23160369

FAQ

What are the physical and chemical properties of 17-Hydroxy-19-norpregna-4,9-diene-3,20-dione (CAS: 14340-01-3)?

17-Hydroxy-19-norpregna-4,9-diene-3,20-dione is a solid with a crystalline form. Its molecular weight is approximately 368.43 g/mol. It is poorly soluble in water but soluble in organic solvents like methanol and ethanol. Chemically, it is a steroid compound with limited reactivity under normal conditions but can undergo oxidation and degradation with exposure to air and light.

How is 17-Hydroxy-19-norpregna-4,9-diene-3,20-dione (CAS: 14340-01-3) typically synthesized?

17-Hydroxy-19-norpregna-4,9-diene-3,20-dione is typically synthesized through the 17-hydroxylation of 19-norpregna-4,9-diene-3,20-dione using a suitable enzymatic or chemical method. Commonly used catalysts include ruthenium complexes or oxygen. The reaction yields are usually around 85-90%, with good selectivity for the desired product.

What industries use 17-Hydroxy-19-norpregna-4,9-diene-3,20-dione (CAS: 14340-01-3)?

17-Hydroxy-19-norpregna-4,9-diene-3,20-dione is primarily used in the pharmaceutical industry for the synthesis of progestins and other steroid hormones. It also finds applications in the agricultural sector as an animal feed additive. Additionally, it is used in some biochemical and research settings for specific studies involving steroid chemistry.

What precautions should be taken when handling 17-Hydroxy-19-norpregna-4,9-diene-3,20-dione (CAS: 14340-01-3)?

When handling 17-Hydroxy-19-norpregna-4,9-diene-3,20-dione, it is important to use personal protective equipment (PPE) such as gloves and safety goggles. Store it in a cool, dry place away from direct sunlight and heat sources. In case of a spill, use appropriate absorbents and follow local waste disposal regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.

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