(2R)-2-(Trifluoromethyl)oxirane | CAS No. 143142-90-9

Q: What regulatory guidelines apply to (2R)-2-(Trifluoromethyl)oxirane (CAS: 143142-90-9)?

The compound (2R)-2-(Trifluoromethyl)oxirane (CAS: 143142-90-9) is classified under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) as a Category 2 Oxidizing Agent. It is subject to the European Union's Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) regulation, which requires manufacturers and importers to register substances with the European Chemicals Agency (ECHA) if they are produced or imported in quantities exceeding 1 tonne per year. The FDA and EPA may also have specific requirements related to its handling and disposal, particularly if it is used in pharmaceutical or industrial applications.

Q: Are there alternatives to (2R)-2-(Trifluoromethyl)oxirane (CAS: 143142-90-9) in synthesis?

There are alternative reagents that can be used in synthesis instead of (2R)-2-(Trifluoromethyl)oxirane (CAS: 143142-90-9), such as trifluoromethylated epoxides or other fluoroalkylating agents. Common substitutes include perfluoromethyl triflate or trifluoromethyl chloromethyl ether, which can serve similar purposes in organic synthesis, depending on the specific reaction conditions and desired products.

Q: What is the market or research trend for (2R)-2-(Trifluoromethyl)oxirane (CAS: 143142-90-9)?

The market and research trends for (2R)-2-(Trifluoromethyl)oxirane (CAS: 143142-90-9) are driven by its applications in pharmaceuticals, agrochemicals, and as a key intermediate in fluorine chemistry. Recent research focuses on its use in developing novel drugs and pesticides. Market trends indicate increasing demand due to advancements in fluorinated molecules for various industrial uses, while research continues to explore its potential in new applications, such as in materials science and environmental remediation.

Q: How should waste containing (2R)-2-(Trifluoromethyl)oxirane (CAS: 143142-90-9) be handled?

Waste containing (2R)-2-(Trifluoromethyl)oxirane (CAS: 143142-90-9) should be collected in appropriate, leak-proof containers and stored in a well-ventilated area away from sources of ignition. It should be disposed of according to local hazardous waste regulations, typically through professional waste disposal services. Incineration is a common method for disposal, but it must be conducted under controlled conditions to minimize environmental impact. Proper environmental protection measures, such as the use of personal protective equipment and monitoring of emissions, are crucial during handling and disposal to ensure safety and compliance with regulations.

(2R)-2-(Trifluoromethyl)oxirane

Basic Information

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CAS Number

143142-90-9

Molecular Formula

C3H3F3O

Molecular Weight

112.05 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Electronic Chemicals Semiconductor Materials Etchants

Water Treatment Chemicals Disinfectants Chlorine Compounds

Basic Physical Properties

Boiling Point

25-32 °C

Density

1.294 g/mL at 25 °C

Refractive Index

n20/D <1.300

SMILES

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C1C(O1)C(F)(F)F

InChI

InChI=1S/C3H3F3O/c4-3(5,6)2-1-7-2/h2H,1H2/t2-/m1/s1

InChIKey

AQZRARFZZMGLHL-UWTATZPHSA-N

LogP

0.9475

Topological Polar Surface Area

12.53 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

76.7

Safety Information

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Hazard Statement

H224 Extremely flammable liquid and vapor
Flammable liquids

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

J-007749
(R)-(+)-3,3,3-Trifluoro-1,2-epoxypropane, 97%
EN300-200927
R-(+)-2-TRIFLUOROMETHYLOXIRANE,97
AKOS032958222
W11990
R-(+)-3,3,3-Trifluoro-1,2-epoxypropane
(2R)-(+)-3,3,3-Trifluoro-1,2-propenoxide
DTXSID401303893
(R)-2-trifluoromethyl-oxirane
(R)-2-(trifluoromethyl)oxirane
143142-90-9
5,5 inverted exclamation mark -(1-MethylEthylidene)bis1,1 inverted exclamation mark -(bisphenyl)-2-ol
(2R)-2-(trifluoromethyl)oxirane
MFCD08276876
SCHEMBL309609
(R)-(+)-2-(Trifluoromethyl)oxirane
R-(+)-2-TRIFLUOROMETHYLOXIRANE, 97
r-(+)-2-Trifluoromethyloxirane,97%
(2R)-2-(Trifluoromethyl)oxirane (ee)
(R)-(+)-3,3,3-Trifluoro-1,2-epoxypropane
AS-54996
r-trifluoromethyloxirane
Oxirane,2-(trifluoromethyl)-, (2R)-
(R)-(+)-2-Trifluoromethyloxirane
(R)-(-)-(Trifluormethyl)oxiran
(R)-(+)-(Trifluoromethyl)oxirane
(R)-(+)-1,1,1-trifluoro-2,3-epoxypropane
(R)-1,1,1-trifluoro-2,3-epoxypropane

MDL Number

MFCD08276876

FAQ

What regulatory guidelines apply to (2R)-2-(Trifluoromethyl)oxirane (CAS: 143142-90-9)?

The compound (2R)-2-(Trifluoromethyl)oxirane (CAS: 143142-90-9) is classified under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) as a Category 2 Oxidizing Agent. It is subject to the European Union's Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) regulation, which requires manufacturers and importers to register substances with the European Chemicals Agency (ECHA) if they are produced or imported in quantities exceeding 1 tonne per year. The FDA and EPA may also have specific requirements related to its handling and disposal, particularly if it is used in pharmaceutical or industrial applications.

Are there alternatives to (2R)-2-(Trifluoromethyl)oxirane (CAS: 143142-90-9) in synthesis?

There are alternative reagents that can be used in synthesis instead of (2R)-2-(Trifluoromethyl)oxirane (CAS: 143142-90-9), such as trifluoromethylated epoxides or other fluoroalkylating agents. Common substitutes include perfluoromethyl triflate or trifluoromethyl chloromethyl ether, which can serve similar purposes in organic synthesis, depending on the specific reaction conditions and desired products.

What is the market or research trend for (2R)-2-(Trifluoromethyl)oxirane (CAS: 143142-90-9)?

The market and research trends for (2R)-2-(Trifluoromethyl)oxirane (CAS: 143142-90-9) are driven by its applications in pharmaceuticals, agrochemicals, and as a key intermediate in fluorine chemistry. Recent research focuses on its use in developing novel drugs and pesticides. Market trends indicate increasing demand due to advancements in fluorinated molecules for various industrial uses, while research continues to explore its potential in new applications, such as in materials science and environmental remediation.

How should waste containing (2R)-2-(Trifluoromethyl)oxirane (CAS: 143142-90-9) be handled?

Waste containing (2R)-2-(Trifluoromethyl)oxirane (CAS: 143142-90-9) should be collected in appropriate, leak-proof containers and stored in a well-ventilated area away from sources of ignition. It should be disposed of according to local hazardous waste regulations, typically through professional waste disposal services. Incineration is a common method for disposal, but it must be conducted under controlled conditions to minimize environmental impact. Proper environmental protection measures, such as the use of personal protective equipment and monitoring of emissions, are crucial during handling and disposal to ensure safety and compliance with regulations.