1-Hexadecanamine | CAS No. 143-27-1

Q: What are the physical and chemical properties of 1-Hexadecanamine (CAS: 143-27-1)?

1-Hexadecanamine (CAS: 143-27-1) is a colorless, flammable liquid at room temperature. Its molecular weight is approximately 238.45 g/mol. It has a solubility of about 10 g/L in water and is highly soluble in organic solvents. Chemically, it is a primary amine with reactive properties, making it useful in various applications.

Q: How is 1-Hexadecanamine (CAS: 143-27-1) typically synthesized?

1-Hexadecanamine (CAS: 143-27-1) can be synthesized through the amination of hexadecanoic acid using a primary amine source and a suitable catalyst, such as sodium hydride. This process typically yields a high selectivity and good yield.

Q: What industries use 1-Hexadecanamine (CAS: 143-27-1)?

1-Hexadecanamine (CAS: 143-27-1) is widely used in the pharmaceutical industry for drug formulations, in the polymer industry for surfactant applications, and in sensor technology for its reactivity and solubility properties.

Q: What precautions should be taken when handling 1-Hexadecanamine (CAS: 143-27-1)?

When handling 1-Hexadecanamine (CAS: 143-27-1), wear appropriate personal protective equipment (PPE) such as gloves and goggles. Use in a well-ventilated area or fume hood. Store in a cool, dry place away from heat sources. In case of spill, use appropriate spill response materials and follow safety data sheet (SDS) guidelines for disposal.

1-Hexadecanamine

Basic Information

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CAS Number

143-27-1

Molecular Formula

C16H35N

Molecular Weight

241.46 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Melting Point

43-45 °C

Boiling Point

330 °C

Refractive Index

1.4496

Vapor Pressure

<1 mmHg ( 20 °C)

SMILES

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CCCCCCCCCCCCCCCCN

InChI

InChI=1S/C16H35N/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17/h2-17H2,1H3

InChIKey

FJLUATLTXUNBOT-UHFFFAOYSA-N

LogP

5.4264000000000046

pKa

10.63(at 25℃)

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

123

Safety Information

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GHS Hazard Pictograms

H314

H400

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

H400 Very toxic to aquatic life
Hazardous to the aquatic environment, acute hazard

Hazard Class

Class 8 Class 8

Synonyms & References

English

1-Hexadecylamine
1-Aminohexadecane~Cetylamine
n-Hexadecylamine
Cetylamine
1-Aminohexadecane
Hexadecyl amine
1-Hexadecanamine
1-AMinohexadecane
Alamine 6
Amine 16D
AMine C16
Armeen 16D
Cetylamin
Hexyldecylamine
Monohexadecylamine
n-Cetylamine
Nissan Amine PB
NSC 8489
Palmitamine
Palmityl amine
HAD
Hexadecan-1-amine
HDA
AminePB
Armeen 16
alamine6d
alamine6
armeen16d
Hexadecylamine
Palmitylamine
Alamine 6D

MDL Number

MFCD00008158

Customs Code

29211980

FAQ

What are the physical and chemical properties of 1-Hexadecanamine (CAS: 143-27-1)?

1-Hexadecanamine (CAS: 143-27-1) is a colorless, flammable liquid at room temperature. Its molecular weight is approximately 238.45 g/mol. It has a solubility of about 10 g/L in water and is highly soluble in organic solvents. Chemically, it is a primary amine with reactive properties, making it useful in various applications.

How is 1-Hexadecanamine (CAS: 143-27-1) typically synthesized?

1-Hexadecanamine (CAS: 143-27-1) can be synthesized through the amination of hexadecanoic acid using a primary amine source and a suitable catalyst, such as sodium hydride. This process typically yields a high selectivity and good yield.

What industries use 1-Hexadecanamine (CAS: 143-27-1)?

1-Hexadecanamine (CAS: 143-27-1) is widely used in the pharmaceutical industry for drug formulations, in the polymer industry for surfactant applications, and in sensor technology for its reactivity and solubility properties.

What precautions should be taken when handling 1-Hexadecanamine (CAS: 143-27-1)?

When handling 1-Hexadecanamine (CAS: 143-27-1), wear appropriate personal protective equipment (PPE) such as gloves and goggles. Use in a well-ventilated area or fume hood. Store in a cool, dry place away from heat sources. In case of spill, use appropriate spill response materials and follow safety data sheet (SDS) guidelines for disposal.