tert-butyl N-[(2R)-1-{[1,1'-biphenyl]-4-yl}-3-hydroxypropan-2-yl]carbamate | CAS No. 1426129-50-1

tert-butyl N-[(2R)-1-{[1,1'-biphenyl]-4-yl}-3-hydroxypropan-2-yl]carbamate

Basic Information

CAS Number

1426129-50-1

Molecular Formula

C20H25NO3

Molecular Weight

327.42 g/mol

AD

Basic Physical Properties

CC(C)(C)OC(=O)NC(CC1=CC=C(C=C1)C2=CC=CC=C2)CO

InChI

InChI=1S/C20H25NO3/c1-20(2,3)24-19(23)21-18(14-22)13-15-9-11-17(12-10-15)16-7-5-4-6-8-16/h4-12,18,22H,13-14H2,1-3H3,(H,21,23)/t18-/m1/s1

InChIKey

TYQICOFAZDVKMK-GOSISDBHSA-N

LogP

3.7817000000000025

Topological Polar Surface Area

58.56 Ų

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

377

Synonyms & References

English

  • AKOS027307888
  • (R)-t-Butyl 1-(biphenyl-4-yl)-3-hydroxypropan-2-ylcarbamate
  • (R)-TERT-BUTYL 1-(BIPHENYL-4-YL)-3-HYDROXYPROPAN-2-YLCARBAMATE
  • SC5054
  • (R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbaMate; (R)-tert-butyl(1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
  • (r)-2-(t-butoxycarbonylamino)-3-(biphenyl-4-yl)-propan-1-ol
  • TYQICOFAZDVKMK-GOSISDBHSA-N
  • A856770
  • (R)-tert-butyl-(1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
  • (R)-tert-butyl(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
  • (R)-tert-butyl(1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
  • MFCD28359221
  • (R)-tert-butyl (1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
  • [(R)-2-(4-Biphenylyl)-1-(hydroxymethyl)ethyl]carbamic acid tert-butyl ester
  • N-[(1R)-2-[1,1'-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]-carbamic Acid1,1-Dimethylethyl Ester
  • tert-butyl N-[(2R)-1-hydroxy-3-(4-phenylphenyl)propan-2-yl]carbamate
  • AC-28983
  • BHC12950
  • DS-11243
  • 1426129-50-1
  • N-[(1R)-2-[1,1'-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]carbamic acid 1,1-dimethylethyl ester
  • SCHEMBL15521493
  • CS-0009327
  • AM85577
  • (R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbaMate
  • (R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
  • (R)-tert-butyl-(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
  • Carbamic acid, N-​[(1R)​-​2-​[1,​1'-​biphenyl]​-​4-​yl-​1-​(hydroxymethyl)​ethyl]​-​, 1,​1-​dimethylethyl ester
  • LCZ696 InteMediate
  • Carbamic acid, N-?[(1R)?-?2-?[1,?1'-?biphenyl]?-?4-?yl-?1-?(hydroxymethyl)?ethyl]?-?, 1,?1-?dimethylethyl ester
  • N-[(1R)-2-[1,1'-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]carbamic acid tert-butyl ester

MDL Number

MFCD28359221

FAQ

What is tert-butyl N-[(2R)-1-{[1,1'-biphenyl]-4-yl}-3-hydroxypropan-2-yl]carbamate (CAS: 1426129-50-1)?

Tert-butyl N-[(2R)-1-{[1,1'-biphenyl]-4-yl}-3-hydroxypropan-2-yl]carbamate (CAS: 1426129-50-1) is a chemical compound featuring a carbamate group, a tert-butyl moiety, and a stereochemically defined (2R) configuration linked to a biphenyl ring. Its molecular formula is C19H24O3N, and it is typically characterized by stability under standard conditions, with applications in specialized chemical research and pharmaceutical development.

What are the main uses of tert-butyl N-[(2R)-1-{[1,1'-biphenyl]-4-yl}-3-hydroxypropan-2-yl]carbamate (CAS: 1426129-50-1)?

This compound is primarily used in pharmaceutical research as an intermediate for drug discovery and development, particularly in compounds targeting enzyme inhibition or receptor modulation. It also finds applications in organic synthesis and industrial chemistry due to its functional groups and structural versatility, though specific industrial uses are not widely documented in public sources.

Is tert-butyl N-[(2R)-1-{[1,1'-biphenyl]-4-yl}-3-hydroxypropan-2-yl]carbamate (CAS: 1426129-50-1) safe?

Safety data for tert-butyl N-[(2R)-1-{[1,1'-biphenyl]-4-yl}-3-hydroxypropan-2-yl]carbamate (CAS: 1426129-50-1) is limited. General handling precautions include avoiding skin contact, inhalation, and ingestion. It should be treated as a chemical with potential toxicity, requiring proper protective equipment and adherence to safety protocols. Always consult a safety data sheet (SDS) for specific guidelines.

How should tert-butyl N-[(2R)-1-{[1,1'-biphenyl]-4-yl}-3-hydroxypropan-2-yl]carbamate (CAS: 1426129-50-1) be stored?

Tert-butyl N-[(2R)-1-{[1,1'-biphenyl]-4-yl}-3-hydroxypropan-2-yl]carbamate (CAS: 1426129-50-1) should be stored in a cool, dry place (ideally below 25°C), in airtight containers to prevent moisture exposure. It is sensitive to light, so storage in dark conditions is recommended. Ensure proper ventilation and avoid contact with incompatible substances to maintain stability and safety.

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