Bydureon | CAS No. 141758-74-9

Bydureon

Basic Information

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CAS Number

141758-74-9

Molecular Formula

C184H282N50O60S

Molecular Weight

4187 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NCC(=O)NCC(=O)N3CCCC3C(=O)NC(CO)C(=O)NC(CO)C(=O)NCC(=O)NC(C)C(=O)N4CCCC4C(=O)N5CCCC5C(=O)N6CCCC6C(=O)NC(CO)C(=O)N)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CCC(=O)N)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC8=CC=CC=C8)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CCC(=O)O)NC(=O)CNC(=O)C(CC9=CNC=N9)N

InChI

InChI=1S/C184H282N50O60S/c1-16-94(10)147(178(289)213-114(52-58-144(257)258)163(274)218-121(73-101-77-195-105-39-24-23-38-103(101)105)168(279)215-116(68-90(2)3)165(276)205-107(41-26-28-61-186)158(269)219-122(75-134(189)243)154(265)198-79-135(244)196-83-139(248)231-63-30-43-129(231)175(286)225-127(87-238)174(285)223-125(85-236)155(266)200-80-136(245)202-96(12)181(292)233-65-32-45-131(233)183(294)234-66-33-46-132(234)182(293)232-64-31-44-130(232)176(287)222-124(84-235)150(190)261)229-170(281)119(71-99-34-19-17-20-35-99)217-166(277)117(69-91(4)5)214-159(270)108(42-29-62-194-184(191)192)212-177(288)146(93(8)9)228-151(262)95(11)203-156(267)111(49-55-141(251)252)208-161(272)112(50-56-142(253)254)209-162(273)113(51-57-143(255)256)210-164(275)115(59-67-295-15)211-160(271)110(47-53-133(188)242)207-157(268)106(40-25-27-60-185)206-172(283)126(86-237)224-167(278)118(70-92(6)7)216-169(280)123(76-145(259)260)220-173(284)128(88-239)226-180(291)149(98(14)241)230-171(282)120(72-100-36-21-18-22-37-100)221-179(290)148(97(13)240)227-138(247)82-199-153(264)109(48-54-140(249)250)204-137(246)81-197-152(263)104(187)74-102-78-193-89-201-102/h17-24,34-39,77-78,89-98,104,106-132,146-149,195,235-241H,16,25-33,40-76,79-88,185-187H2,1-15H3,(H2,188,242)(H2,189,243)(H2,190,261)(H,193,201)(H,196,244)(H,197,263)(H,198,265)(H,199,264)(H,200,266)(H,202,245)(H,203,267)(H,204,246)(H,205,276)(H,206,283)(H,207,268)(H,208,272)(H,209,273)(H,210,275)(H,211,271)(H,212,288)(H,213,289)(H,214,270)(H,215,279)(H,216,280)(H,217,277)(H,218,274)(H,219,269)(H,220,284)(H,221,290)(H,222,287)(H,223,285)(H,224,278)(H,225,286)(H,226,291)(H,227,247)(H,228,262)(H,229,281)(H,230,282)(H,249,250)(H,251,252)(H,253,254)(H,255,256)(H,257,258)(H,259,260)(H4,191,192,194)/t94-,95-,96-,97+,98+,104-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,146-,147-,148-,149-/m0/s1

InChIKey

HTQBXNHDCUEHJF-XWLPCZSASA-N

LogP

-20.604330000000342

Topological Polar Surface Area

1749.7499999999989 Å²

Hydrogen Bond Donor/Acceptor

65 / 110

Complexity

10300

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

AKOS015994651
ITCA 650
AC2993A
HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS
DA 3091
UNII-9P1872D4OL
(Ser-39 = C-terminal amide)
LY 2148568
Bydureon
9P1872D4OL
Exenatide [USAN:INN:BAN:JAN]
AC 2993A
Exendin 4
141758-74-9
Exendin 3 (Heloderma horridum), 2-glycine-3-L-glutamic acid-
Exendin-4
PT302
HSDB 7789
C184H282N50O60S
SCHEMBL14634818
HS-2012
HB3157
AC002993
Y-100006
Exenatide; Exendin-4
AC 2993
Exenatide
Bydureon Pen
exendin-4
H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
Exenatide Acetate

MDL Number

MFCD08704781

FAQ

What is Bydureon (CAS: 141758-74-9)?

Bydureon, with the CAS number 141758-74-9, is a glucagon-like peptide-1 (GLP-1) receptor agonist used primarily in the treatment of type 2 diabetes. It is a synthetic peptide drug that mimics the action of GLP-1, a hormone involved in regulating blood sugar levels. Bydureon has a molecular formula of C53H77N15O13S and is known for its long-acting properties, administered once weekly.

What are the main uses of Bydureon (CAS: 141758-74-9)?

Bydureon (CAS: 141758-74-9) is mainly used as a medication for managing type 2 diabetes. It helps to increase insulin secretion, reduce glucagon release, and slow gastric emptying, thereby improving blood glucose control. Additionally, it may be used in combination with other diabetes medications to enhance therapeutic outcomes. Its applications also extend to research in metabolic disorders and drug development.

Is Bydureon (CAS: 141758-74-9) safe?

Bydureon (CAS: 141758-74-9) is generally considered safe when used as directed. It is approved by the FDA for its therapeutic use in type 2 diabetes. However, like all medications, it may cause side effects such as nausea, vomiting, or hypoglycemia. Proper handling and administration under medical supervision are essential to ensure safety and minimize risks.

How should Bydureon (CAS: 141758-74-9) be stored?

Bydureon (CAS: 141758-74-9) should be stored in a cool, dry place away from direct light. It is typically kept at room temperature (15°C to 25°C) and protected from moisture. The medication should be stored in its original container to maintain stability and prevent degradation. Always check the expiration date and follow the manufacturer's guidelines for storage conditions.