Trans-1,2-cyclohexanedicarboxylic Anhydride

Basic Information

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CAS Number

14166-21-3

Molecular Formula

C8H10O3

Molecular Weight

154.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

144.0 to 149.0 deg-C

Boiling Point

35-36°C

Density

1.18

Flash Point

143℃

Refractive Index

1.536

SMILES

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C1CCC2C(C1)C(=O)OC2=O

InChI

InChI=1S/C8H10O3/c9-7-5-3-1-2-4-6(5)8(10)11-7/h5-6H,1-4H2/t5-,6-/m1/s1

InChIKey

MUTGBJKUEZFXGO-PHDIDXHHSA-N

LogP

0.8761999999999999

Topological Polar Surface Area

43.370000000000005 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

187

Safety Information

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Hazard Statement

H317 May cause an allergic skin reaction
Sensitization, Skin

H318 Causes serious eye damage
Serious eye damage/eye irritation

H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Sensitization, respiratory

Synonyms & References

English

A807788
Hexahydro-2-benzofuran-1,3-dione, trans
D89440
CS-0155411
DTXSID60449118
(+)-trans-1,2-Cyclohexanedicarboxylic Anhydride
(3aR,7aR)-hexahydro-2-benzofuran-1,3-dione
trans-Hexahydroisobenzofuran-1,3-dione
AS-63623
trans-Cyclohexane-1,2-dicarboxylic anhydride
14166-21-3
1,3-Isobenzofurandione, hexahydro-, (3aR,7aR)-rel-
MFCD00674194
(3aR,7aR)-hexahydroisobenzofuran-1,3-dione
trans-Hexahydrophthalic anhydride
71749-03-6
(3aR,7aR)-3a,4,5,6,7,7a-hexahydro-2-benzofuran-1,3-dione
racemic trans-hexahydroisobenzofuran-1,3-dione
AKOS015833100
1,3-Isobenzofurandione, hexahydro-, (3aR,7aR)-
(+/-)-trans-1,2-Cyclohexanedicarboxylic Anhydride
(3aR,7aR)-3a,4,5,6,7,7a-hexahydroisobenzofuran-1,3-dione
T71260
Cyclohexanedicarboxylicanhydride; 98%
MFCD00064345
trans-1,2-Cyclohexanedicarboxylic anhydride
(3aR,7aR)-octahydro-2-benzofuran-1,3-dione
SCHEMBL598374
1,3-Isobenzofurandione, hexahydro-, trans-
AKOS015900342
rel-(3aR,7aR)-Hexahydroisobenzofuran-1,3-dione

MDL Number

MFCD00064345

Customs Code

2932999099

FAQ

What are the physical and chemical properties of Trans-1,2-cyclohexanedicarboxylic Anhydride (CAS: 14166-21-3)?

Trans-1,2-cyclohexanedicarboxylic anhydride is a crystalline solid with a molecular weight of approximately 194.23 g/mol. It is slightly soluble in water and highly soluble in organic solvents. Chemically, it is highly reactive, particularly with primary amines and hydroxyl groups, making it useful in a variety of chemical reactions.

How is Trans-1,2-cyclohexanedicarboxylic Anhydride (CAS: 14166-21-3) typically synthesized?

Trans-1,2-cyclohexanedicarboxylic anhydride can be synthesized through the dehydration of 1,2-cyclohexanedicarboxylic acid. Commonly, this involves heating the acid at elevated temperatures in the presence of a drying agent like molecular sieves, leading to a high yield of the anhydride.

What industries use Trans-1,2-cyclohexanedicarboxylic Anhydride (CAS: 14166-21-3)?

Trans-1,2-cyclohexanedicarboxylic anhydride is utilized in the pharmaceutical, polymer, and sensor industries. It is a key intermediate in the synthesis of various chemical compounds and polymers, and it can also be used in the production of organic semiconductors and sensors.

What precautions should be taken when handling Trans-1,2-cyclohexanedicarboxylic Anhydride (CAS: 14166-21-3)?

Handling Trans-1,2-cyclohexanedicarboxylic anhydride requires caution. It should be stored in a cool, well-ventilated area away from incompatible materials. Use appropriate personal protective equipment (PPE) such as gloves and goggles. Work should be conducted in a fume hood due to its reactivity. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.