2-Fluoro-6-hydroxybenzonitrile

Basic Information

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CAS Number

140675-43-0

Molecular Formula

C7H4FNO

Molecular Weight

126.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Nitriles

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

155.0 to 159.0 deg-C

Boiling Point

257.5°Cat760mmHg

Density

1.34

Flash Point

109.5°C

Refractive Index

1.56

SMILES

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C1=CC(=C(C(=C1)F)C#N)O

InChI

InChI=1S/C7H4FNO/c8-6-2-1-3-7(10)5(6)4-9/h1-3,10H

InChIKey

YEBHNFDMNFHZFF-UHFFFAOYSA-N

LogP

1.8397199999999998

Topological Polar Surface Area

20.23 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

162

Safety Information

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GHS Hazard Pictograms

H331

H302

H312

H315

H319

H335

Hazard Statement

H331 Toxic if inhaled
Acute toxicity, inhalation

H302 Harmful if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

6-fluorosalicylonitrile
AC-4070
EG-0028
CS-W018318
140675-43-0
CL8166
CCG-302513
DTXSID00382515
SCHEMBL30978
YEBHNFDMNFHZFF-UHFFFAOYSA-N
2-fluoro-6-hydroxybenzonitrile
AM20061167
6-Fluoro-2-hydroxybenzonitrile
2-hydroxy-6-fluorobenzonitrile
SY021121
2-FLUORO-6-HYDROXYBENZONITRLE
2-Fluoro-6-hydroxybenzonitrile, AldrichCPR
6-Fluorosalicylonitrile;2-Fluoro-6-hydroxybenzonitrile;2-Cyano-3-fluorophenol
2-Cyano-3-Fluorophenol
FT-0643319
AKOS005254993
Z425420618
2-Fluoro-6-hydroxy-benzonitrile
A20954
EN300-43317
Benzonitrile, 2-fluoro-6-hydroxy-
MFCD03428592
F0985
2-Fluoro-6-hydroxybenzonitrile
2-Cyano-3-fluorophenol
6-FLUOROSALICYLONITRILE

MDL Number

MFCD03428592

Customs Code

2926909090

FAQ

What regulatory guidelines apply to 2-Fluoro-6-hydroxybenzonitrile (CAS: 140675-43-0)?

2-Fluoro-6-hydroxybenzonitrile (CAS: 140675-43-0) is regulated under the Globally Harmonized System of Classification and Labeling of Chemicals (GHS), which includes health, environmental, and physical hazard classifications. In the European Union, it is also subject to REACH regulations, requiring manufacturers and importers to register substances if they exceed certain tonnage thresholds. Additionally, the Food and Drug Administration (FDA) and Environmental Protection Agency (EPA) may have specific guidelines for its use, storage, and disposal in the United States.

Are there alternatives to 2-Fluoro-6-hydroxybenzonitrile (CAS: 140675-43-0) in synthesis?

Several alternatives to 2-Fluoro-6-hydroxybenzonitrile (CAS: 140675-43-0) can be used in synthesis, such as fluorobenzonitrile or hydroxy-benzonitrile, depending on the desired substituent pattern. Researchers often explore isomers and structural analogs to achieve similar or altered properties. Common alternative reagents include nitriles with different substituents or other functional groups that can be introduced through various chemical reactions.

What is the market or research trend for 2-Fluoro-6-hydroxybenzonitrile (CAS: 140675-43-0)?

The market and research trends for 2-Fluoro-6-hydroxybenzonitrile (CAS: 140675-43-0) are focused on its use as a precursor in the synthesis of pharmaceuticals and agrochemicals. Recent studies have shown increasing interest in its role in developing new drug candidates and crop protection agents. Market trends indicate growing demand in regions with robust chemical and pharmaceutical industries. Research is also exploring its potential in materials science and environmental remediation.

How should waste containing 2-Fluoro-6-hydroxybenzonitrile (CAS: 140675-43-0) be handled?

Waste containing 2-Fluoro-6-hydroxybenzonitrile (CAS: 140675-43-0) should be managed according to local and international regulations. Collection should be done in appropriate containers, ensuring that the waste is not reactive or explosive. For disposal, incineration is a common method, but professional waste disposal services are recommended to ensure compliance with environmental protection standards. Proper labeling and documentation of the waste are essential to avoid environmental contamination and health risks.