(4R)-4-methyl-1,3-dioxolane

Basic Information

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CAS Number

1405-69-2

Molecular Formula

C4H8O2

Molecular Weight

88.11 g/mol

EINECS

215-783-6

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Density

1.3400

SMILES

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CC1COCO1

InChI

InChI=1S/C4H8O2/c1-4-2-5-3-6-4/h4H,2-3H2,1H3/t4-/m1/s1

InChIKey

SBUOHGKIOVRDKY-SCSAIBSYSA-N

LogP

0.3792

Topological Polar Surface Area

18.46 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

44.8

Synonyms & References

English

(R)-4-methyl-1,3-dioxolane
(4R)-4-methyl-1,3-dioxolane
1405-69-2
Avidin from egg white
1648543-28-5
lyophilized powder, 10-15 units/mg protein (E1%/280), inverted exclamation markY98%
avidins
AVIDIN, HEN EGG WHITE
AVIDINE
AVIDIN, EGG WHITE
AVIDIN CHICKEN EGG WHITE
AVIDIN
AVIDIN-ACETYL
IMMUNOPURE AVIDIN
Avidin
Avidins
Neutralite Avidin
Avidin, Egg White
AVIDIN, CHICKEN EGG WHITE
glycoproteins, avidins
Aids104218
Aids-104218
Anti-biotin protein

MDL Number

MFCD00130572

EC Number

215-783-6

Customs Code

3504009000

FAQ

What are the physical and chemical properties of (4R)-4-methyl-1,3-dioxolane (CAS: 1405-69-2)?

The compound (4R)-4-methyl-1,3-dioxolane has a white crystalline form with a molecular weight of approximately 102.12 g/mol. It is moderately soluble in common organic solvents and poorly soluble in water. Chemically, it is quite reactive, particularly in nucleophilic substitution reactions. Its reactivity and solubility make it useful in various synthetic applications.

How is (4R)-4-methyl-1,3-dioxolane (CAS: 1405-69-2) typically synthesized?

(4R)-4-Methyl-1,3-dioxolane can be synthesized via a condensation reaction of 2-methyl-1,3-diketone with a suitable nucleophile. Commonly, the diketone is reacted with a primary alcohol in the presence of a catalyst such as sodium hydroxide or potassium carbonate. The yield is typically around 70-80% with high selectivity for the desired enantiomer.

What industries use (4R)-4-methyl-1,3-dioxolane (CAS: 1405-69-2)?

(4R)-4-Methyl-1,3-dioxolane is widely used in the pharmaceutical industry for the synthesis of chiral intermediates. It is also utilized in the polymer industry as a monomer for preparing various polymers. Additionally, it is employed in the manufacturing of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling (4R)-4-methyl-1,3-dioxolane (CAS: 1405-69-2)?

When handling (4R)-4-methyl-1,3-dioxolane, it is important to use appropriate personal protective equipment (PPE) such as gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be handled promptly with appropriate absorbents, and the substance should be stored in a sealed container away from heat sources. Always consult the Safety Data Sheet (SDS) for detailed handling guidelines.