Capreomycin sulfate

Basic Information

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CAS Number

1405-37-4

Molecular Formula

C24H44N14O12S

Molecular Weight

752.8 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

No data available

Boiling Point

1290.8°C at 760 mmHg

Density

1.3400

Water Solubility

Freely soluble in water

Flash Point

>110°(230°F)

Solubility

H2O: soluble50mg/mL

Vapor Pressure

No data available

Specific Rotation

-32 ~ -25° (c=5, H2O)

SMILES

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C1CN=C(NC1C2C(=O)NCC(C(=O)NC(C(=O)NC(C(=O)NC(=CNC(=O)N)C(=O)N2)CNC(=O)C(CCCN)N)CO)N)N.OS(=O)(=O)O

InChI

InChI=1S/C24H42N14O8.H2O4S/c25-4-1-2-10(26)17(40)32-7-13-19(42)34-14(8-33-24(29)46)20(43)38-16(12-3-5-30-23(28)37-12)22(45)31-6-11(27)18(41)36-15(9-39)21(44)35-13;1-5(2,3)4/h8,10-13,15-16,39H,1-7,9,25-27H2,(H,31,45)(H,32,40)(H,34,42)(H,35,44)(H,36,41)(H,38,43)(H3,28,30,37)(H3,29,33,46);(H2,1,2,3,4)/b14-8-;/t10-,11-,12?,13-,15-,16-;/m0./s1

InChIKey

LFFNIXQXRKNZCE-XYHGUWSSSA-N

LogP

-2.00290

Complexity

1310

Safety Information

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GHS Hazard Pictograms

H302

H312

H332

H360

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H332 Harmful if inhaled
Acute toxicity, inhalation

H360 May damage fertility or the unborn child
Reproductive toxicity

Synonyms & References

English

AKOS025310793
NS00021009
Capastat sulfate
CAPREOMYCIN, SULFATE (SALT)
(2S)-2,5-Diamino-N-(((2S,5S,11S,15S,Z)-15-amino-11-(2-amino-3,4,5,6-tetrahydropyrimidin-4-yl)-2-(hydroxymethyl)-3,6,9,12,16-pentaoxo-8-(ureidomethylene)-1,4,7,10,13-pentaazacyclohexadecan-5-yl)methyl)pentanamide sulfate
A911135
1405-37-4
CAPREOMYCINSULFATE
CCG-270439
capreomycin sulfate from streptomyces*capreolus
Capreomycin Sulphate
Capreomycin Sulfate
Capreomycin sulfate from Streptomyces capreolus
Capreomycin (sulfate)
Capromycin sulfate
Potency 700 - 1050 &micro
Capreomycin sulfate salt
caprocin
Capreomicin sulphate
CapreoMycin Sulfate API
capreomycin,sulfate(salt)
capreomycin sulfate sterile
Capreomycin
Sulfuric acid
Capromycinsulfate
Capreomycin/Sulfuric acid
(2S)-2,5-Diamino-N-[[(2S,5S,11S,15S)-15-amino-11-(2-amino-1,4,5,6-tetrahydropyrimidin-6-yl)-8-[(carb
H-Dap(1)-DL-Ser-Dap(2)-Dha(ureido)-DL-Arg-(1).H-Orn-(2).H2SO4
capastat sulfate
CAPREOMYCIN SULFATE
CAPREOMYCIN SULPHATE

MDL Number

MFCD00079032

FAQ

What regulatory guidelines apply to Capreomycin sulfate (CAS: 1405-37-4)?

Capreomycin sulfate (CAS: 1405-37-4) is subject to regulatory guidelines such as the Globally Harmonized System of Classification and Labeling of Chemicals (GHS), registration under the European Union's REACH regulation, and requirements by the U.S. FDA and EPA. This includes proper labeling, storage, and handling practices to ensure worker safety and environmental protection.

Are there alternatives to Capreomycin sulfate (CAS: 1405-37-4) in synthesis?

Alternatives to Capreomycin sulfate (CAS: 1405-37-4) in synthesis include other aminoglycoside antibiotics like amikacin, kanamycin, and streptomycin. These alternatives offer similar antimicrobial properties but may differ in terms of efficacy, toxicity, and resistance patterns.

What is the market or research trend for Capreomycin sulfate (CAS: 1405-37-4)?

The market for Capreomycin sulfate (CAS: 1405-37-4) is experiencing steady growth due to its effectiveness against multidrug-resistant tuberculosis. Ongoing research focuses on optimizing its therapeutic index and exploring its use in combination therapies. Market dynamics include increased demand from emerging markets and the development of new formulations.

How should waste containing Capreomycin sulfate (CAS: 1405-37-4) be handled?

Waste containing Capreomycin sulfate (CAS: 1405-37-4) should be collected, stored, and disposed of in accordance with hazardous waste regulations. Proper handling includes neutralization to reduce toxicity, followed by incineration or professional waste disposal to ensure environmental safety and compliance with local and international environmental protection standards.