(1R,2R,3S,4R,6S)-4,6-Diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside sulfate (1:1)

Basic Information

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CAS Number

1405-10-3

Molecular Formula

C23H48N6O17S

Molecular Weight

712.73 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

>360°C

Boiling Point

1046.1°C at 760 mmHg

Water Solubility

Soluble in water

Flash Point

56℃

Solubility

H2O: 50 mg/mL As a stock solution. Stock solutions should be filter sterilized and stored at 2-8°C. Stable at 37°C for 5 days.

Refractive Index

56 ° (C=10, H2O)

Specific Rotation

+53° ~ +59° (c=10, H2O)

SMILES

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C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)N)OC3C(C(C(O3)CO)OC4C(C(C(C(O4)CN)O)O)N)O)O)N.OS(=O)(=O)O

InChI

InChI=1S/C23H46N6O13.H2O4S/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;1-5(2,3)4/h5-23,30-36H,1-4,24-29H2;(H2,1,2,3,4)/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;/m1./s1

InChIKey

OIXVKQDWLFHVGR-WQDIDPJDSA-N

LogP

-9.548100000000018

Topological Polar Surface Area

427.71 Å²

Hydrogen Bond Donor/Acceptor

21 / 23

Complexity

953

Safety Information

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GHS Hazard Pictograms

H317

H334

Hazard Statement

H317 May cause an allergic skin reaction
Sensitization, Skin

H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Sensitization, respiratory

Synonyms & References

English

SCHEMBL373681
D-Streptamine, O-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(1-3)-O-beta-D-ribofuranosyl-(1-5)-O-(2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1-4))-2-deoxy-, sulfate (salt)
Isofra (TN)
CHEBI:53636
OIXVKQDWLFHVGR-WQDIDPJDSA-N
HMS2095O18
MFCD00150827
Fradiomycin sulfate
Neomycin sulphate, Antibiotic for Culture Media Use Only
Neomycin B sulfate
(2S,3S,4R,5R,6R)-5-Amino-2-(aminomethyl)-6-(((2R,3S,4R,5S)-5-(((1R,2R,3S,5R,6S)-3,5-diamino-2-(((2R,3R,4R,5S,6R)-3-amino-6-(aminomethyl)-4,5-dihydroxytetrahydro-2H-pyran-2-yl)oxy)-6-hydroxycyclohexyl)oxy)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl)oxy)tetrahydro-2H-pyran-3,4-diol xsulfate
(1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside sulfate
EINECS 248-770-9
Neomycin Sulfate hydrate
KS-1358
F0649
Neoamine,(S)
NEOMYCIN SULFATE
1405-10-3
AKOS016340327
Neomycin B sulphate
Framycetin sulphate
WHO Third International Standard for Neomycin
D07994
Framycetin sulfate
Neomycin sulfate, USP grade
Neomycin sulfate for microbiological assay
Neomycin Trisulfate Hydrate
1404-04-2 (acid)
28002-70-2
Neomycin Sulphate B