(2S)-1-(6-Amino-9H-purin-9-yl)-2-propanol

Basic Information

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CAS Number

14047-27-9

Molecular Formula

C8H11N5O

Molecular Weight

193.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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C[C@@H](Cn1cnc2c1ncnc2N)O

InChI

InChI=1S/C8H11N5O/c1-5(14)2-13-4-12-6-7(9)10-3-11-8(6)13/h3-5,14H,2H2,1H3,(H2,9,10,11)/t5-/m0/s1

InChIKey

MJZYTEBKXLVLMY-YFKPBYRVSA-N

LogP

-0.21069999999999994

Topological Polar Surface Area

89.85000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 6

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(αS)-6-amino-α-methyl-9H-Purine-9-ethanol
(S)-9-[2-(Hydroxypropyl] Adenine
(S)-(-)-9-(2-Hydroxypropyl)adenine
(S)-1-(6-Amino-9H-purin-9-yl)propan-2-ol
9H-Purine-9-ethanol, 6-amino-a-methyl-, (S)-
(2S)-1-(6-aminopurin-9-yl)propan-2-ol
Tenofovir Related Compound 9
L-(+)-9-(2-Hydroxypropyl)adenine
Tenofovir impurity A
(S)-1-(6-amino-9H-purin-9-yl)propan-2-ol

MDL Number

MFCD20698392

FAQ

What regulatory guidelines apply to (2S)-1-(6-Amino-9H-purin-9-yl)-2-propanol (CAS: 14047-27-9)?

This compound (2S)-1-(6-Amino-9H-purin-9-yl)-2-propanol (CAS: 14047-27-9) falls under the scope of the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), which includes classification for health hazards, environmental hazards, and flammability. In the European Union, it is regulated under the Registration, Evaluation, Authorization, and Restriction of Chemicals (REACH) regulation. Additionally, the United States Environmental Protection Agency (EPA) and the Food and Drug Administration (FDA) have specific guidelines for its handling and registration, particularly in pharmaceutical and chemical manufacturing environments.

Are there alternatives to (2S)-1-(6-Amino-9H-purin-9-yl)-2-propanol (CAS: 14047-27-9) in synthesis?

For synthesis, there are several alternatives to (2S)-1-(6-Amino-9H-purin-9-yl)-2-propanol (CAS: 14047-27-9), such as (2R)-1-(6-Amino-9H-purin-9-yl)-2-propanol and related purine derivatives. These alternatives can be used depending on the specific requirements of the synthesis, including reactivity and desired properties. Common alternative reagents include purine derivatives and their isomers, which may offer similar functionality with different structural features.

What is the market or research trend for (2S)-1-(6-Amino-9H-purin-9-yl)-2-propanol (CAS: 14047-27-9)?

The market for (2S)-1-(6-Amino-9H-purin-9-yl)-2-propanol (CAS: 14047-27-9) is primarily driven by its application in pharmaceuticals, particularly as a potential drug candidate for treating various diseases. Research trends include its exploration as an antiviral and anti-inflammatory agent. Market trends show increasing demand due to its potential in therapeutic applications, and ongoing research is focused on optimizing its pharmacological properties and reducing toxicity.

How should waste containing (2S)-1-(6-Amino-9H-purin-9-yl)-2-propanol (CAS: 14047-27-9) be handled?

Waste containing (2S)-1-(6-Amino-9H-purin-9-yl)-2-propanol (CAS: 14047-27-9) should be collected and stored in appropriate containers to prevent contamination and leakage. Disposal should follow hazardous waste regulations, typically involving incineration or professional waste disposal services. Environmental protection measures include proper containment to prevent runoff and ensure worker safety. Compliance with local and national environmental regulations is crucial to minimize environmental impact.