2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-Yl)benzenesulfonamide | CAS No. 1403764-72-6

2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-Yl)benzenesulfonamide

Basic Information

CAS Number

1403764-72-6

Molecular Formula

C16H17N3O4S

Molecular Weight

347.4 g/mol

AD

Basic Physical Properties

CN1CC2=C(C=CC(=C2)NS(=O)(=O)C3=CC=CC=C3OC)NC1=O

InChI

InChI=1S/C16H17N3O4S/c1-19-10-11-9-12(7-8-13(11)17-16(19)20)18-24(21,22)15-6-4-3-5-14(15)23-2/h3-9,18H,10H2,1-2H3,(H,17,20)

InChIKey

TXZPMHLMPKIUGK-UHFFFAOYSA-N

LogP

2.4733

Topological Polar Surface Area

87.74 Ų

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

562

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • PFI-1
  • 2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide
  • PF-6405761
  • PFI 1
  • PFI-1 (PF-6405761)
  • 2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydro-quinazolin-6-yl)-bezenesulfonamide
  • PF-06405761
  • EX-A480
  • CHEBI:95079
  • PFI-1(PF-6405761)
  • 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzene-1-sulfonamide
  • NCGC00344624-13
  • Z1730011930
  • PFI-1, >=98% (HPLC)
  • 2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfon amide
  • Q27088338
  • NSC777448
  • NSC-777448
  • CS-1362
  • HMS3426C13
  • SCHEMBL14721611
  • GTPL7523
  • J-007379
  • CHEMBL2179387
  • NSC768123
  • AKOS024458163
  • PFI-1 (PF-06405761)
  • GLXC-04441
  • 2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-Yl)benzenesulfonamide
  • HY-16586
  • AS-16355

MDL Number

MFCD22580416

FAQ

What are the physical and chemical properties of 2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-Yl)benzenesulfonamide (CAS: 1403764-72-6)?

2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-Yl)benzenesulfonamide is a crystalline compound with a molecular weight of approximately 438.47 g/mol. It has a low to moderate solubility in common organic solvents. Chemically, it is stable under normal conditions but may react with strong acids and bases. It is insoluble in water.

How is 2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-Yl)benzenesulfonamide (CAS: 1403764-72-6) typically synthesized?

2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-Yl)benzenesulfonamide is synthesized via multi-step organic reactions, typically involving the synthesis of a 2-oxo-1,2,3,4-tetrahydroquinazoline derivative followed by sulfonation and methylation steps. The reactions are carried out under mild conditions using appropriate catalysts and solvents.

What industries use 2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-Yl)benzenesulfonamide (CAS: 1403764-72-6)?

2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-Yl)benzenesulfonamide is used in the pharmaceutical industry for its potential as a medicinal compound. It may also find applications in sensor technology and as a precursor in the synthesis of other organic compounds.

What precautions should be taken when handling 2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-Yl)benzenesulfonamide (CAS: 1403764-72-6)?

When handling 2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-Yl)benzenesulfonamide, it is important to wear protective gloves and goggles. Store it in a cool, dry place away from direct sunlight. Use in a well-ventilated area or under a fume hood due to its potential reactivity. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.

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