Tazemetostat | CAS No. 1403254-99-8

Tazemetostat

Basic Information

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CAS Number

1403254-99-8

Molecular Formula

C34H44N4O4

Molecular Weight

572.75 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CCN(C1CCOCC1)C2=CC(=CC(=C2C)C(=O)NCC3=C(C=C(NC3=O)C)C)C4=CC=C(C=C4)CN5CCOCC5

InChI

InChI=1S/C34H44N4O4/c1-5-38(29-10-14-41-15-11-29)32-20-28(27-8-6-26(7-9-27)22-37-12-16-42-17-13-37)19-30(25(32)4)33(39)35-21-31-23(2)18-24(3)36-34(31)40/h6-9,18-20,29H,5,10-17,21-22H2,1-4H3,(H,35,39)(H,36,40)

InChIKey

NSQSAUGJQHDYNO-UHFFFAOYSA-N

LogP

4.734660000000005

Topological Polar Surface Area

86.9 Å²

Hydrogen Bond Donor/Acceptor

2 / 8

Complexity

992

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-3-[ethyl(oxan-4-yl)amino]-2-methyl-5-[4-(morpholin-4-ylmethyl)phenyl]benzamide
EPZ-6438
E-7438
EPZ-7438
EPZ 6438
EPZ-6438 (E-7438)
N-[(1,2-Dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-5-[ethyl(tetrahydro-2H-pyran-4-yl)amino]-4-methyl-4'-(4-morpholinylmethyl)-[1,1'-biphenyl]-3-carboxamide
Tazemetostat
Tazemetostat (EPZ-6438)
EPZ-6438 (E7438)
N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4'-(morpholinomethyl)-[1,1'-biphenyl]-3-carboxamide
S7128,E7438
EPZ6438
Q40W93WPE1
E7438
(1,1'-Biphenyl)-3-carboxamide, N-((1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl)-5-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4'-(4-morpholinylmethyl)-
N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-3-[ethyl(oxan-4-yl)amino]-2-methyl-5-[4-(m
NCGC00381562-01
1403254-99-8
N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl) methyl)-5-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4'-(morpholinomethyl)-[1,1'-biphenyl]-3-carboxamide
N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4'-(morpholinomethyl)-(1,1'-biphenyl)-3-carboxamide
Tazemetostat [USAN]
Tazemetostatum
DTXSID201025831
CCG-264672
NSC-777109
C34H44N4O4
BCP07409
N-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-5-[ethyl(oxan-4-yl)amino]-4-methyl-4'-[(morpholin-4-yl)methyl]-[1,1'-biphenyl]-3-carboxamide
s7128
J-690163

MDL Number

MFCD24849415

FAQ

What regulatory guidelines apply to Tazemetostat (CAS: 1403254-99-8)?

Tazemetostat (CAS: 1403254-99-8) is subject to various regulatory guidelines including GHS classification, REACH regulations, and FDA/EPA requirements. It is classified as a pharmaceutical drug, which means it must comply with strict safety, efficacy, and manufacturing standards.

Are there alternatives to Tazemetostat (CAS: 1403254-99-8) in synthesis?

Alternative reagents and analogs to Tazemetostat (CAS: 1403254-99-8) can be considered depending on the specific synthesis route. For instance, dimethyl tazemetostat and related compounds may serve as alternatives, providing similar functionalities in different chemical contexts.

What is the market or research trend for Tazemetostat (CAS: 1403254-99-8)?

The market and research trends for Tazemetostat (CAS: 1403254-99-8) are focused on its application in treating hematological malignancies. There is ongoing research to explore its efficacy in other disease areas, with a growing interest in its potential as a targeted therapy.

How should waste containing Tazemetostat (CAS: 1403254-99-8) be handled?

Waste containing Tazemetostat (CAS: 1403254-99-8) should be collected in appropriate containers and disposed of through professional waste disposal services. Incineration is a common method, but environmental protection precautions must be taken to ensure compliance with local regulations and minimize environmental impact.