5-Fluoro-1-(4-fluoro-3-{[4-(2-pyrimidinyl)-1-piperazinyl]carbonyl}benzyl)-2,4(1H,3H)-quinazolinedione | CAS No. 1401682-78-7
5-Fluoro-1-(4-fluoro-3-{[4-(2-pyrimidinyl)-1-piperazinyl]carbonyl}benzyl)-2,4(1H,3H)-quinazolinedione
Basic Information
CAS Number
1401682-78-7
Molecular Formula
C24H20F2N6O3
Molecular Weight
478.45 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- Senaparib
- MNZ4OP95CF
- 5-fluoro-1-[[4-fluoro-3-(4-pyrimidin-2-ylpiperazine-1-carbonyl)phenyl]methyl]quinazoline-2,4-dione
- Senaparib [INN]
- GTPL11199
- IMP4297
- 2,4(1H,3H)-Quinazolinedione, 5-fluoro-1-((4-fluoro-3-((4-(2-pyrimidinyl)-1-piperazinyl)carbonyl)phenyl)methyl)-
- 5-Fluoro-1-((4-fluoro-3-((4-(2-pyrimidinyl)-1-piperazinyl)carbonyl)phenyl)methyl)-2,4(1H,3H)-quinazolinedione
FAQ
What regulatory guidelines apply to 5-Fluoro-1-(4-fluoro-3-{[4-(2-pyrimidinyl)-1-piperazinyl]carbonyl}benzyl)-2,4(1H,3H)-quinazolinedione (CAS: 1401682-78-7)?
5-Fluoro-1-(4-fluoro-3-{[4-(2-pyrimidinyl)-1-piperazinyl]carbonyl}benzyl)-2,4(1H,3H)-quinazolinedione (CAS: 1401682-78-7) falls under the purview of the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) for hazardous chemicals, requiring appropriate hazard communication. It is also subject to REACH regulations in the European Union, which require pre-market registration and risk assessment. For FDA and EPA related requirements, the compound may require specific evaluations based on its intended use and potential environmental impact.
Are there alternatives to 5-Fluoro-1-(4-fluoro-3-{[4-(2-pyrimidinyl)-1-piperazinyl]carbonyl}benzyl)-2,4(1H,3H)-quinazolinedione (CAS: 1401682-78-7) in synthesis?
While 5-Fluoro-1-(4-fluoro-3-{[4-(2-pyrimidinyl)-1-piperazinyl]carbonyl}benzyl)-2,4(1H,3H)-quinazolinedione (CAS: 1401682-78-7) is a specialized compound, alternative reagents such as related quinazolines or other substituted pyrimidinyl compounds can be explored. These alternatives can vary in reactivity and selectivity, and their use depends on the specific synthetic route and desired outcome.
What is the market or research trend for 5-Fluoro-1-(4-fluoro-3-{[4-(2-pyrimidinyl)-1-piperazinyl]carbonyl}benzyl)-2,4(1H,3H)-quinazolinedione (CAS: 1401682-78-7)?
The market for 5-Fluoro-1-(4-fluoro-3-{[4-(2-pyrimidinyl)-1-piperazinyl]carbonyl}benzyl)-2,4(1H,3H)-quinazolinedione (CAS: 1401682-78-7) is niche but growing, driven by its use in pharmaceutical research for potential anti-tumor activity. Research trends include its evaluation in combination therapies and the exploration of its pharmacokinetic and pharmacodynamic properties. Market trends suggest increasing demand from academic and industrial research institutions.
How should waste containing 5-Fluoro-1-(4-fluoro-3-{[4-(2-pyrimidinyl)-1-piperazinyl]carbonyl}benzyl)-2,4(1H,3H)-quinazolinedione (CAS: 1401682-78-7) be handled?
Waste containing 5-Fluoro-1-(4-fluoro-3-{[4-(2-pyrimidinyl)-1-piperazinyl]carbonyl}benzyl)-2,4(1H,3H)-quinazolinedione (CAS: 1401682-78-7) should be collected in appropriate containers and stored under controlled conditions to prevent degradation. Disposal should comply with local regulations and may require incineration or professional waste disposal services. Environmental protection measures should include proper containment to prevent accidental release and ensure safe handling practices.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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Supplier Information
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