(4-Chlorophenyl)acetonitrile

Basic Information

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CAS Number

140-53-4

Molecular Formula

C8H6ClN

Molecular Weight

151.59 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Nitriles

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

25-28 °C

Boiling Point

267°C

Solubility

0.3g/l

Refractive Index

1.5415-1.5435

SMILES

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C1=CC(=CC=C1CC#N)Cl

InChI

InChI=1S/C8H6ClN/c9-8-3-1-7(2-4-8)5-6-10/h1-4H,5H2

InChIKey

IVYMIRMKXZAHRV-UHFFFAOYSA-N

LogP

2.40608

Complexity

139

Safety Information

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GHS Hazard Pictograms

H301

H311

H315

H319

H331

H335

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H311 Toxic in contact with skin
Acute toxicity, dermal

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H331 Toxic if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

Z57131037
DTXCID8030263
EINECS 205-418-9
4-chlorophenylacetonitriie
P-CHLORBENZYLNITRILE
A23320
p-chlorophenyl-acetonitrile
4-CHLOROBENZYL NITRILE
MFCD00001918
NCGC00357129-01
K2K7AKZ2Z7
NSC 49108
4-Chlor-benzyl-cyanid [German]
4-Chlorobenzyl--d4 Cyanide
4-09-00-01676 (Beilstein Handbook Reference)
W-108204
F0001-0482
AKOS000119502
HY-W017390
4-Chlorophenylacetonitrile
PYRIMETHAMINE IMPURITY C [EP IMPURITY]
2-(4-chlorophenyl)-acetonitrile
SCHEMBL38192
C03679
D70879
p-Chloro phenyl acetonitrile
CAS-140-53-4
PB48045
(4-chlorophenyl)-acetonitrile
4-chlorophenyl acetonitrile
EN300-18340

MDL Number

MFCD00001918

Customs Code

29269095

FAQ

What is (4-Chlorophenyl)acetonitrile (CAS: 140-53-4)?

(4-Chlorophenyl)acetonitrile, with the CAS number 140-53-4, is an organic compound consisting of a nitrile group attached to an acetyl group, which is further connected to a 4-chlorophenyl ring. It is a colorless liquid with a characteristic odor and is known for its reactivity in organic synthesis. The compound has a molecular formula of C8H7ClN and is commonly used as an intermediate in the production of various pharmaceuticals and agrochemicals.

What are the main uses of (4-Chlorophenyl)acetonitrile (CAS: 140-53-4)?

(4-Chlorophenyl)acetonitrile (CAS: 140-53-4) is primarily used in the pharmaceutical industry as a building block for synthesizing drugs and medicinal compounds. It also finds applications in agrochemicals, particularly in the development of pesticides. Additionally, it is used in research settings for organic synthesis and as a reagent in chemical reactions requiring nitrile functionality.

Is (4-Chlorophenyl)acetonitrile (CAS: 140-53-4) safe?

(4-Chlorophenyl)acetonitrile (CAS: 140-53-4) is considered hazardous due to its potential to cause irritation and toxicity. It should be handled with appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Safety data sheets (SDS) recommend avoiding inhalation and skin contact, and ensuring proper ventilation when working with this compound in industrial or laboratory settings.

How should (4-Chlorophenyl)acetonitrile (CAS: 140-53-4) be stored?

(4-Chlorophenyl)acetonitrile (CAS: 140-53-4) should be stored in a cool, dry, and well-ventilated area, away from light and moisture. It is typically kept in a sealed, airtight container made of glass or high-density polyethylene (HDPE). Storage conditions should maintain a temperature below 25°C and avoid exposure to air or water to ensure stability and prevent degradation.