N-Trityl Candesartan

Basic Information

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CAS Number

139481-72-4

Molecular Formula

C43H34N6O3

Molecular Weight

682.78 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

Powder

Melting Point

163-165 ºC

Boiling Point

908.6°C at 760 mmHg

SMILES

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CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NN=NN5C(C6=CC=CC=C6)(C7=CC=CC=C7)C8=CC=CC=C8)C(=O)O

InChI

InChI=1S/C43H34N6O3/c1-2-52-42-44-38-24-14-23-37(41(50)51)39(38)48(42)29-30-25-27-31(28-26-30)35-21-12-13-22-36(35)40-45-46-47-49(40)43(32-15-6-3-7-16-32,33-17-8-4-9-18-33)34-19-10-5-11-20-34/h3-28H,2,29H2,1H3,(H,50,51)

InChIKey

VBMKOTRJWPIKMG-UHFFFAOYSA-N

LogP

8.342200000000007

Topological Polar Surface Area

107.95 Å²

Hydrogen Bond Donor/Acceptor

1 / 9

Complexity

1090

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

2-ethoxy-1-[[2'-(N-triphenylmethyltetrazol-5-yl)-biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid
2-ethoxy-1-((2'-(1-trityl-1h-tetrazol-5-yl)biphenyl-4-yl)methyl)-1h-benzo[d]imidazole-7-carboxylic acid
FT-0652450
2-Ethoxy-1-[[(2 inverted exclamation mark -(1-triphenylmethyl-1H-tetrazol-5-yl)biphenyl-4-yl-)methyl]benzimidazole-7-carboxylicacid
DS-1153
Trityl candesartan
AKOS015896035
C43H34N6O3
AB44950
139481-72-4
AC-1477
J-007282
AM90290
2-ethoxy-3-[[4-[2-(1-trityltetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid
2-Ethoxy-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylic acid
CS-W006659
VBMKOTRJWPIKMG-UHFFFAOYSA-N
MFCD08436154
2-ethoxy-1-{[2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid
2-Ethoxy-1-[[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid
Tritylcandesartan
2-Ethoxy-1-{[2'-(1-trityl-1H-tetrazol-5-yl)-4-biphenylyl]methyl}-1H-benzimidazole-7-carboxylic acid
2-ethoxy-1-[[2'-(1-triphenylmethyl-1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid
2-ethoxy-1-[{2'-[1-(trityl)-1H-tetrazol-5-yl]-biphenyl-4-yl}-methyl]-1H-benzimidazole-7-carboxylic acid
2-ethoxy-1-({2'-[1-(triphenylmethyl)-1H-1,2,3,4-tetrazol-5-yl]-[1,1'-biphenyl]-4-yl}methyl)-1H-1,3-benzodiazole-7-carboxylic acid
(Trityl candesartan)2-Ethoxy-1-[[2-(2-Triphenyl Methyl)-2H-Tetrazole-5-YL](1,1-Biphenyl)-4-YL]Methyl]Benzimidazole-2-Carboxylic Acid
2-ethoxy-l-[[2'-(N-triphenylmethyl-tetrazol-5-yl) biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid
BCP12746
SCHEMBL498030
1H-BENZIMIDAZOLE-7-CARBOXYLIC ACID, 2-ETHOXY-1-[[2'-[1-(TRIPHENYLMETHYL)-1H-TETRAZOL-5-YL][1,1'-BIPHENYL]-4-YL]METHYL]-
DTXSID40437932

MDL Number

MFCD08436154

Customs Code

2933990090

FAQ

What is N-Trityl Candesartan (CAS: 139481-72-4)?

N-Trityl Candesartan is a derivative of candesartan, a selective angiotensin II receptor antagonist used in the treatment of hypertension and heart failure. Its chemical formula is C36H37NO3. This compound is characterized by its stability and efficacy in pharmaceutical applications.

What are the main uses of N-Trityl Candesartan (CAS: 139481-72-4)?

N-Trityl Candesartan is primarily used in the pharmaceutical industry for the treatment of hypertension and heart failure. It is a key component in the formulation of antihypertensive medications that help manage blood pressure by blocking the effects of angiotensin II, a hormone that narrows blood vessels.

Is N-Trityl Candesartan (CAS: 139481-72-4) safe?

N-Trityl Candesartan is generally considered safe when used as directed. However, it is important to follow the prescribed dosage and instructions from healthcare providers to minimize potential side effects. Patients should consult a healthcare professional if they experience any adverse reactions.

How should N-Trityl Candesartan (CAS: 139481-72-4) be stored?

N-Trityl Candesartan should be stored in a cool, dry place away from direct sunlight and moisture. The container should be tightly sealed to prevent moisture absorption. It is recommended to store it at a temperature not exceeding 25°C to maintain its stability and effectiveness.