Candesartan Cilexetil Impurity 8

Basic Information

View in Editor

CAS Number

139481-28-0

Molecular Formula

C22H17N3O4

Molecular Weight

387.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Nitriles

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Powder

Boiling Point

595.5°C at 760 mmHg

Density

1.33±0.1 g/cm3 (20 ºC 760 Torr),

Solubility

Insuluble (6.2E-5 g/L) (25 ºC),

SMILES

View in Editor

COC(=O)C1=C(C(=CC=C1)[N+](=O)[O-])NCC2=CC=C(C=C2)C3=CC=CC=C3C#N

InChI

InChI=1S/C22H17N3O4/c1-29-22(26)19-7-4-8-20(25(27)28)21(19)24-14-15-9-11-16(12-10-15)18-6-3-2-5-17(18)13-23/h2-12,24H,14H2,1H3

InChIKey

ZIRAEAZVSCADHC-UHFFFAOYSA-N

LogP

5.12838

Complexity

617

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

C72573
Methyl 2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)-3-nitrobenzoate
FT-0665374
Methyl 2-{[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]amino}-3-nitrobenzoate
Methyl 2-[[(2'-Cyanobiphenyl-4-yl)methyl]amino]-3-nitrobenzoate
2-[[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]amino]-3-nitro-benzoic Acid Methyl Ester
methyl 2-[[4-(2-cyanophenyl)phenyl]methylamino]-3-nitrobenzoate
DS-4301
BCP12903
Benzoicacid, 2-[[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]amino]-3-nitro-methylester
AKOS015912152
methyl 2-[[(2'-cyano-biphenyl-4-yl)methyl]amino]-3-nitro-benzoate
CS-0150896
C22H17N3O4
AC-26430
139481-28-0
A886001
ZIRAEAZVSCADHC-UHFFFAOYSA-N
DTXSID00576391
methyl 2-[N-(2'-cyanobiphenyl-4-yl)methylamino]-3-nitrobenzoate
methyl 2[[(2'-cyanobiphenyl-4-yl)methyl]amino]-3-nitrobenzoate
SCHEMBL2598198
Benzoic acid,2-[[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]amino]-3-nitro-,methyl ester
MFCD09029084
benzoic acid, 2-[[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]amino]-3-nitro-methyl ester
BENZOIC acid, 2-[[(2'-CYANO[1,1'-BIPHENYL]-4-YL)METHYL]AMINO]-3-NITRO-METHYL ESTER
Methyl 2-[[(2'-cyanobiphenyl-4-yl)methyl]amino]-3-nitrobenzoate
AK109346
Methyl 2-((2'-cyanobiphenyl-4-yl)methylamino)-3-nitrobenzoate
BEN131
Methyl2-((2'-cyanobiphenyl-4-yl)methylamino)-3-nitrobenzoate

MDL Number

MFCD09029084

Customs Code

2926909090

FAQ

What regulatory guidelines apply to Candesartan Cilexetil Impurity 8 (CAS: 139481-28-0)?

Candesartan Cilexetil Impurity 8 (CAS: 139481-28-0) is subject to various regulatory guidelines including GHS (Globally Harmonized System of Classification and Labelling of Chemicals) for hazard communication, REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) for EU market compliance, and FDA (Food and Drug Administration) and EPA (Environmental Protection Agency) requirements for safety and environmental protection in the US. Compliance with these regulations ensures safe handling and disposal of the impurity.

Are there alternatives to Candesartan Cilexetil Impurity 8 (CAS: 139481-28-0) in synthesis?

Alternatives to Candesartan Cilexetil Impurity 8 (CAS: 139481-28-0) in synthesis include the use of more stable or less reactive impurities, or employing alternative reagents and solvents that can reduce the formation of such impurities. Common substitutes include using purer starting materials and optimizing reaction conditions to minimize by-products.

What is the market or research trend for Candesartan Cilexetil Impurity 8 (CAS: 139481-28-0)?

The market trend for Candesartan Cilexetil Impurity 8 (CAS: 139481-28-0) reflects a focus on drug safety and regulatory compliance. Research trends are centered on developing more efficient purification methods and alternative impurities to ensure drug quality. The increasing emphasis on pharmacovigilance and the reduction of impurities in pharmaceuticals drives the need for detailed analysis and monitoring of such impurities.

How should waste containing Candesartan Cilexetil Impurity 8 (CAS: 139481-28-0) be handled?

Waste containing Candesartan Cilexetil Impurity 8 (CAS: 139481-28-0) should be collected in appropriate containers and stored in a safe, controlled environment. Proper disposal methods include incineration or professional waste disposal services that adhere to environmental protection regulations. It is crucial to follow local and international guidelines for hazardous waste management to prevent environmental contamination.