Ziprasidone hydrochloride monohydrate

Basic Information

View in Editor

CAS Number

138982-67-9

Molecular Formula

C21H24Cl2N4O2S

Molecular Weight

467.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

No data available

Melting Point

300 ºC

Boiling Point

No data available

Flash Point

No data available

Solubility

DMSO: >10mg/mL

Vapor Pressure

No data available

SMILES

View in Editor

C1CN(CCN1CCC2=C(C=C3C(=C2)CC(=O)N3)Cl)C4=NSC5=CC=CC=C54.O.Cl

InChI

InChI=1S/C21H21ClN4OS.ClH.H2O/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21;;/h1-4,11,13H,5-10,12H2,(H,23,27);1H;1H2

InChIKey

ZCBZSCBNOOIHFP-UHFFFAOYSA-N

LogP

3.4061000000000026

Topological Polar Surface Area

79.97 Å²

Hydrogen Bond Donor/Acceptor

3 / 6

Complexity

573

Safety Information

View Safety Information

Hazard Statement

H317 May cause an allergic skin reaction
Sensitization, Skin

H373 Causes damage to organs through prolonged or repeated exposure
Specific target organ toxicity, repeated exposure

Synonyms & References

English

LP01025
UNII-216X081ORU
ZIPRASIDONE HYDROCHLORIDE [USP-RS]
NCGC00186050-01
AKOS015961662
SCHEMBL122875
BZ164577
CP-880591
5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one hydrochloride monohydrate
Ziprasidone hydrochloride, United States Pharmacopeia (USP) Reference Standard
ZIPRASIDONE HYDROCHLORIDE MONOHYDRATE [MI]
138982-67-9
Ziprasidone for system suitability 1, European Pharmacopoeia (EP) Reference Standard
ZIPRASIDONE HYDROCHLORIDE [MART.]
Ziprasidone hydrochloride hydrate (JAN)
Ziprasidone Hydrochloride Monohydrate 1.0 mg/ml in Methanol (as anhydrous free base)
2H-Indol-2-one, 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydro-, monohydrochloride, monohydrate
NCGC00261710-01
ZIPRASIDONE HYDROCHLORIDE [ORANGE BOOK]
ziprasidone hydrochloride, monohydrate
Geodon (TN)
Ziprasidone hydrochloride monohydrate, >=98% (HPLC), solid
CS-1198
ME-2112
Ziprasidone hydrochloride [USAN]
ZIPRASIDONE HYDROCHLORIDE [USP MONOGRAPH]
2H-INDOL-2-ONE, 5-(2-(4-(1,2-BENZISOTHIAZOL-3-YL)-1-PIPERAZINYL)ETHYL)-6-CHLORO-1,3-DIHYDRO-, HYDROCHLORIDE, HYDRATE (1:1:1)
AS-16359
CCG-222329
FT-0600387
5-(2-(4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-onehydrochloridehydrate

MDL Number

MFCD00921885

Customs Code

2934999090

FAQ

What is Ziprasidone hydrochloride monohydrate (CAS: 138982-67-9)?

Ziprasidone hydrochloride monohydrate (CAS: 138982-67-9) is a white or off-white powder with a molecular formula of C25H27N5·HCl·H2O. It is primarily used as an antipsychotic medication in psychiatric treatment. It has anti-inflammatory and anti-oxidant properties and is known for its ability to stabilize mood and reduce psychotic symptoms.

What are the main uses of Ziprasidone hydrochloride monohydrate (CAS: 138982-67-9)?

Ziprasidone hydrochloride monohydrate (CAS: 138982-67-9) is mainly used as an oral antipsychotic medication to treat schizophrenia and bipolar disorder. It is effective in managing symptoms such as hallucinations, delusions, and manic episodes. Additionally, it is used in the treatment of depressive disorders and other mood disorders.

Is Ziprasidone hydrochloride monohydrate (CAS: 138982-67-9) safe?

Ziprasidone hydrochloride monohydrate (CAS: 138982-67-9) is generally considered safe when used under medical supervision. However, it can cause side effects such as weight gain, drowsiness, and extrapyramidal symptoms. It is important to follow the prescribed dosage and monitor for any adverse reactions. Patients should inform their healthcare provider if they experience any unusual symptoms.

How should Ziprasidone hydrochloride monohydrate (CAS: 138982-67-9) be stored?

Ziprasidone hydrochloride monohydrate (CAS: 138982-67-9) should be stored at a temperature between 15°C and 30°C (59°F to 86°F) in a dry place, protected from light. It should be kept in a tightly closed container to prevent moisture and contamination. Avoid exposure to extreme temperatures and ensure the container is securely sealed to maintain its potency and safety.