(4R)-4-(Ethylamino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide

Basic Information

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CAS Number

138890-62-7

Molecular Formula

C12H21N3O5S3

Molecular Weight

383.52 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Powder

Melting Point

130.0 to 134.0 deg-C

Boiling Point

586.0±60.0°C at 760 mmHg

Density

1.5±0.1 g/cm3

Flash Point

308.2±32.9 °C

Solubility

DMSO: ≥10mg/mL

Refractive Index

1.625

Vapor Pressure

0.0±1.6 mmHg at 25°C

SMILES

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CCN[C@H]1CN(CCCOC)S(=O)(=O)c2sc(cc12)S(=O)(=O)N

InChI

InChI=1S/C12H21N3O5S3/c1-3-14-10-8-15(5-4-6-20-2)23(18,19)12-9(10)7-11(21-12)22(13,16)17/h7,10,14H,3-6,8H2,1-2H3,(H2,13,16,17)/t10-/m0/s1

InChIKey

HCRKCZRJWPKOAR-JTQLQIEISA-N

LogP

0.08690000000000075

Topological Polar Surface Area

118.8 Å²

Hydrogen Bond Donor/Acceptor

3 / 8

Complexity

598

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Sensitiveness

sensitive to heat and humidity

Synonyms & References

English

Brinzolamide
BIRNZOLAMIDE
2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide, (4R)-
2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide, (R)-
AL 4862
Brinlolamide
(R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide
(4R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-Dioxide
(4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-3,4-dihydrothieno[3,2-e]thiazine-6-sulfonamide
AL-4862
(R)-(+)-4-ethylamino-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide-1,1-dioxide
Azopt
Azopt (TN)
Brinzolamide (BRZ)
Brinzolamide [USAN]
(5R)-5-Ethylamino-3-(3-methoxypropyl)-2,2-dioxo-2?6,9-dithia-3-azabicyclo[4.3.0]nona-7,10-diene-8-sulfonamide
(R)-4-(Ethylamino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-Dioxide
(R)- 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide
(R)-4-(ethylamino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide

MDL Number

MFCD08067749

Customs Code

2935009090

FAQ

What is (4R)-4-(Ethylamino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide (CAS: 138890-62-7)?

This compound, with CAS number 138890-62-7, is a thienothiazine derivative containing an ethylamino group and a 3-methoxypropyl group. It is known for its sulfonamide functionality and is typically found in its 1,1-dioxide form. This compound has a complex molecular structure and is often studied for its pharmacological properties, particularly in relation to its potential as a therapeutic agent.

What are the main uses of (4R)-4-(Ethylamino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide (CAS: 138890-62-7)?

The compound is primarily used in pharmaceutical research, especially in the development of drugs targeting neurological and psychiatric conditions. It may also find applications in medicinal chemistry as a potential lead compound for new therapeutic agents. Its unique structure suggests possible use in drug design for treating diseases involving neurotransmitter modulation.

Is (4R)-4-(Ethylamino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide (CAS: 138890-62-7) safe?

Safety of this compound depends on its specific use and exposure conditions. It is generally considered safe when handled properly in controlled environments. However, standard safety precautions should be followed, including the use of personal protective equipment (PPE) and adherence to chemical safety guidelines. Its toxicity profile is not well-documented, but it is advisable to consult safety data sheets (SDS) for detailed information.

How should (4R)-4-(Ethylamino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide (CAS: 138890-62-7) be stored?

This compound should be stored in a cool, dry, and light-protected environment. It is recommended to keep it in a sealed container at a temperature below 25°C and maintain low humidity levels. Avoid exposure to air and moisture to ensure stability and prevent degradation. Always store in a well-ventilated area away from incompatible substances.