1-(1-Piperazinyl)ethanone

Basic Information

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CAS Number

13889-98-0

Molecular Formula

C6H12N2O

Molecular Weight

128.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Powder

Melting Point

31-34 °C

Boiling Point

127-130℃/8mmHg

Water Solubility

Soluble in water 210 g/L (20°C).

Solubility

methanol: soluble1g/10 mL, clear, colorless to faintly greenish-yellow

Refractive Index

1.4880 (estimate)

SMILES

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CC(=O)N1CCNCC1

InChI

InChI=1S/C6H12N2O/c1-6(9)8-4-2-7-3-5-8/h7H,2-5H2,1H3

InChIKey

PKDPUENCROCRCH-UHFFFAOYSA-N

LogP

-0.5619000000000001

Topological Polar Surface Area

32.34 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

108

Safety Information

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GHS Hazard Pictograms

H315

H319

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Sensitiveness

Hygroscopic

Synonyms & References

English

1-(piperazin-1-yl)ethan-1-one
N-Acetylpiperazine
AM20080291
CS-W007382
SCHEMBL5433
NSC39649
1-Acetylpiperazine;N-Acetylpiperazine
acetylpiperazine
1-piperazin-1-yl-ethanone
DTXSID80160833
1-N-acetylpiperazine
1-acetylpiperzine
PKDPUENCROCRCH-UHFFFAOYSA-
SR-01000944788-1
N-acetyl-piperazine
acetyl-piperazine
AKOS000118862
acetyl piperazine
1-Acetylpiperazine
NSC-39649
CHEBI:194598
1-Acetylpiperazine, purum, >=98.0% (GC)
1-(1-piperazinyl)ethanone
PKDPUENCROCRCH-UHFFFAOYSA-N
Piperazine, 1-acetyl-
4-acetylpiperazine
UNII-A64RRE6QT5
N-acetylpiperizine
1-acetyl-piperazine
1-(piperazin-1-yl)ethanone
1-acetylpiperizine

MDL Number

MFCD00058676

Customs Code

2933599090

FAQ

What is 1-(1-Piperazinyl)ethanone (CAS: 13889-98-0)?

1-(1-Piperazinyl)ethanone is a chemical compound with the CAS number 13889-98-0. It is an organic molecule containing a piperazine ring and an acetyl group. This compound is known for its ability to act as a building block in chemical synthesis, particularly in pharmaceutical and medicinal chemistry. It has a molecular formula of C6H11NO2 and is typically a white crystalline solid at room temperature.

What are the main uses of 1-(1-Piperazinyl)ethanone (CAS: 13889-98-0)?

1-(1-Piperazinyl)ethanone is widely used in pharmaceutical research for the synthesis of various drugs and medicinal compounds. It serves as an intermediate in the production of antidepressants, antipsychotics, and other therapeutic agents. Additionally, it has applications in organic chemistry for creating derivatives and in the development of new materials. Its reactivity and structural versatility make it valuable in both academic and industrial settings.

Is 1-(1-Piperazinyl)ethanone (CAS: 13889-98-0) safe?

1-(1-Piperazinyl)ethanone is generally considered safe when handled properly, but it may pose health risks if exposed to high concentrations. It is important to follow standard safety protocols, such as using gloves and ensuring proper ventilation, to minimize inhalation or skin contact. Safety data sheets (SDS) should be consulted for detailed handling and disposal instructions. As with any chemical, it should be used in accordance with regulatory guidelines and safety standards.

How should 1-(1-Piperazinyl)ethanone (CAS: 13889-98-0) be stored?

1-(1-Piperazinyl)ethanone should be stored in a cool, dry, and well-ventilated area, away from direct sunlight. It is recommended to keep it in a sealed container to prevent moisture absorption and degradation. Storage at temperatures below 25°C is ideal for maintaining stability. Always ensure the container is labeled properly and stored in a location that is inaccessible to children and unauthorized personnel.