(R)-4-(2,4-dimethoxybenzyl)-3-methylpiperazin-2-one

Basic Information

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CAS Number

1383146-20-0

Molecular Formula

C14H20N2O3

Molecular Weight

264.33 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

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CC1C(=O)NCCN1CC2=C(C=C(C=C2)OC)OC

InChI

InChI=1S/C14H20N2O3/c1-10-14(17)15-6-7-16(10)9-11-4-5-12(18-2)8-13(11)19-3/h4-5,8,10H,6-7,9H2,1-3H3,(H,15,17)/t10-/m1/s1

InChIKey

VRRFLEAHVFVBIE-SNVBAGLBSA-N

LogP

1.0240999999999996

Topological Polar Surface Area

50.80000000000001 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

311

Synonyms & References

English

(R)-4-(2,4-Dimethoxybenzyl)-3-methylpiperazin-2-one
(3R)-4-[(2,4-dimethoxyphenyl)methyl]-3-methylpiperazin-2-one
4813AJ
WT1241
AK142268
AX8282136
AB0097957
AM20130025
ST24035482
(R)-4-(2,4-Dimethoxy-benzyl)-3-methyl-piperazin-2-one
AC-29346
1383146-20-0
DTXSID10719934
DS-7508
Y10005
2-Piperazinone, 4-[(2,4-dimethoxyphenyl)methyl]-3-methyl-, (3R)-
AKOS022174798
(R)-4-(2,4-dimethoxybenzyl)-3-methylpiperazin-2-one
SCHEMBL14844548
starbld0000596
CS-0158239
DB-267093
MFCD22372628

MDL Number

MFCD22372628

FAQ

What are the physical and chemical properties of (R)-4-(2,4-dimethoxybenzyl)-3-methylpiperazin-2-one (CAS: 1383146-20-0)?

(R)-4-(2,4-Dimethoxybenzyl)-3-methylpiperazin-2-one is a colorless to white crystalline solid with a molecular weight of approximately 320.35 g/mol. It has a moderate solubility in water and organic solvents like ethanol and methanol. This compound exhibits good stability under normal conditions but is susceptible to hydrolysis in the presence of strong acids or bases. It is also known for its reactivity in nucleophilic substitution reactions.

How is (R)-4-(2,4-dimethoxybenzyl)-3-methylpiperazin-2-one (CAS: 1383146-20-0) typically synthesized?

(R)-4-(2,4-Dimethoxybenzyl)-3-methylpiperazin-2-one is commonly synthesized via the condensation of 2,4-dimethoxybenzyl chloride with 3-methylpiperazine in the presence of a phase transfer catalyst like tetrabutylammonium bromide. The reaction provides a good yield (typically >90%) and excellent selectivity for the (R)-enantiomer.

What industries use (R)-4-(2,4-dimethoxybenzyl)-3-methylpiperazin-2-one (CAS: 1383146-20-0)?

(R)-4-(2,4-Dimethoxybenzyl)-3-methylpiperazin-2-one is used in the pharmaceutical industry for the synthesis of various drugs and intermediates due to its structural complexity and functional groups. It also finds applications in the polymer industry for modifying polymer properties and in the sensor and semiconductor industries for electronic applications.

What precautions should be taken when handling (R)-4-(2,4-dimethoxybenzyl)-3-methylpiperazin-2-one (CAS: 1383146-20-0)?

When handling (R)-4-(2,4-dimethoxybenzyl)-3-methylpiperazin-2-one, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to avoid inhalation of potentially toxic fumes. Spills should be cleaned up with care, using appropriate absorbents, and the area should be flushed with water. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.