Levofloxacin hydrate

Basic Information

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CAS Number

138199-71-0

Molecular Formula

C36H42F2N6O9

Molecular Weight

740.76 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

214-216°C

Boiling Point

571.5°Cat760mmHg

Density

1.48

Flash Point

299.4℃

SMILES

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O.C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc4c(=O)c(cn1c24)C(=O)O.C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc4c(=O)c(cn1c24)C(=O)O

InChI

InChI=1S/2C18H20FN3O4.H2O/c2*1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21;/h2*7-8,10H,3-6,9H2,1-2H3,(H,24,25);1H2/t2*10-;/m00./s1

InChIKey

SUIQUYDRLGGZOL-RCWTXCDDSA-N

LogP

2.2633000000000014

Topological Polar Surface Area

181.51999999999998 Å²

Hydrogen Bond Donor/Acceptor

4 / 15

Complexity

634

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H317 May cause an allergic skin reaction
Sensitization, Skin

H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Sensitization, respiratory

H362 May cause harm to breast-fed children
Reproductive toxicity, effects on or via lactation

Synonyms & References

English

(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid hydrate (2:1)
(S)-(-)-Ofloxacine
Levofloxacine
(-)-(s)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7h-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hydrochloride
Levofloxacin hemihydrate
Levofloxacin Hemihidrated
LEVOFLOXACIN HYDROCHLORIDE
Levofloxacin
Levofloxacin hydrate
Levofloxacin Impurity 16
ofloxacin
Ofloxacine
Floxin
Tarivid
Oxaldin
Ofloxacino
Ofloxacinum
Oflocet
Visiren
Ocuflox
OFLX
Exocin
Ofloxacina
Ofloxacin Otic
Floxin otic
Ofloxacina [DCIT]
Ofloxacinum [Latin]
Ofloxacine [French]
Zanocin
Exocine
Flobacin

MDL Number

MFCD07772024

FAQ

What is Levofloxacin hydrate (CAS: 138199-71-0)?

Levofloxacin hydrate (CAS: 138199-71-0) is a crystalline solid and the hydrate form of levofloxacin, a broad-spectrum antibiotic belonging to the fluoroquinolone class. It is commonly used in pharmaceutical formulations and has the chemical formula C18H20FN3O3·H2O. It is soluble in water and exhibits strong antibacterial activity against gram-positive and gram-negative bacteria.

What are the main uses of Levofloxacin hydrate (CAS: 138199-71-0)?

Levofloxacin hydrate (CAS: 138199-71-0) is primarily used in the treatment of bacterial infections such as respiratory tract infections, urinary tract infections, and skin infections. It is also utilized in veterinary medicine and research for its antimicrobial properties. Its effectiveness against a wide range of bacteria makes it a valuable compound in pharmaceutical applications.

Is Levofloxacin hydrate ( CAS: 138199-71-0 ) safe?

Levofloxacin hydrate (CAS: 138199-71-0) is generally considered safe when used as directed in medical and veterinary contexts. However, it may cause side effects such as gastrointestinal discomfort, dizziness, or photosensitivity. Proper handling and adherence to safety guidelines are essential, especially during manufacturing and storage to ensure quality and minimize risks.

How should Levofloxacin hydrate (CAS: 138199-71-0) be stored?

Levofloxacin hydrate (CAS: 138199-71-0) should be stored in a cool, dry place away from direct sunlight. It is typically kept at a temperature between 15°C to 30°C (59°F to 86°F) and should be protected from moisture. Storage in a sealed container ensures stability and maintains the compound's efficacy over time.