2-Methyl-2-propanyl 4-[(methylamino)methyl]-1-piperidinecarboxylate

Basic Information

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CAS Number

138022-02-3

Molecular Formula

C12H24N2O2

Molecular Weight

228.34 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Boiling Point

300.9℃ at 760 mmHg

SMILES

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CC(C)(C)OC(=O)N1CCC(CC1)CNC

InChI

InChI=1S/C12H24N2O2/c1-12(2,3)16-11(15)14-7-5-10(6-8-14)9-13-4/h10,13H,5-9H2,1-4H3

InChIKey

FXEYGOYVUJFORB-UHFFFAOYSA-N

LogP

1.8528999999999998

Topological Polar Surface Area

41.57000000000001 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

228

Synonyms & References

English

EN300-100974
tert-butyl 4-(methylaminomethyl)piperidine-1-carboxylate
AM97538
FT-0647804
FXEYGOYVUJFORB-UHFFFAOYSA-N
DTXSID80620321
138022-02-3
SCHEMBL627965
4-methylaminomethyl-piperidine-1-carboxylic acid tert-butyl-ester
tert-Butyl 4-[(methylamino)methyl]-1-piperidinecarboxylate
4-[(METHYLAMINO)METHYL]PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
SY018028
1-t-butoxycarbonyl-4-[(methylamino)methyl]piperidine
SB33228
2-Methyl-2-propanyl 4-[(methylamino)methyl]-1-piperidinecarboxylate
TS-00585
1-Piperidinecarboxylic acid, 4-[(methylamino)methyl]-, 1,1-dimethylethyl ester
tert-butyl 4-[(methylamino)methyl]-piperidine-1-carboxylate
CS-W003298
A25788
tert-butyl4-((methylamino)methyl)piperidine-1-carboxylate
W-205511
tert-butyl 4-((methylamino)methyl)piperidine-1-carboxylate
MFCD06656629
tert-Butyl 4-[(Methylamino)methyl]piperidine-1-carboxylate
4-(N-Methyl)aminomethyl-1-Boc-piperidine
1-Boc-4-[(Methylamino)methyl]piperidine
4-methylaminomethylpiperidine-1-carboxylic acid tert-butyl ester
4-methylaminomethyl piperidine-1-carboxylic acid tert-butyl ester
4-Methylaminomethyl-piperidine-1-carboxylic acid tert-butyl ester
tert-butyl 4-((methylamino)methyl)piperidine-1-carboxylate;1-Boc-4-[(methylamino)methyl]piperidine

MDL Number

MFCD06656629

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-Methyl-2-propanyl 4-[(methylamino)methyl]-1-piperidinecarboxylate (CAS: 138022-02-3)?

2-Methyl-2-propanyl 4-[(methylamino)methyl]-1-piperidinecarboxylate is a white crystalline compound with a molecular weight of approximately 244.36 g/mol. It is slightly soluble in water and has good solubility in organic solvents such as ethanol and dichloromethane. The compound shows moderate reactivity in basic conditions and is stable under acidic conditions. It is used in pharmaceuticals and as a reagent in organic synthesis.

How is 2-Methyl-2-proanyl 4-[(methylamino)methyl]-1-piperidinecarboxylate (CAS: 138022-02-3) typically synthesized?

2-Methyl-2-proanyl 4-[(methylamino)methyl]-1-piperidinecarboxylate is typically synthesized through a multistep reaction involving the coupling of 2-methyl-2-propanol and 4-(methylaminomethyl)-1-piperidinecarboxylic acid. The reaction uses catalytic amounts of a suitable base, such as triethylamine, and is carried out in an organic solvent like dichloromethane. The yield is typically around 75-80%, and the product is isolated by recrystallization.

What industries use 2-Methyl-2-proanyl 4-[(methylamino)methyl]-1-piperidinecarboxylate (CAS: 138022-02-3)?

2-Methyl-2-proanyl 4-[(methylamino)methyl]-1-piperidinecarboxylate is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drug candidates. It is also used in the chemical industry as a reagent in organic synthesis and as a building block for the preparation of other compounds with specific functional groups.

What precautions should be taken when handling 2-Methyl-2-proanyl 4-[(methylamino)methyl]-1-piperidinecarboxylate (CAS: 138022-02-3)?

When handling 2-Methyl-2-proanyl 4-[(methylamino)methyl]-1-piperidinecarboxylate, it is important to use appropriate personal protective equipment (PPE), including gloves and safety goggles. The compound should be handled in a well-ventilated area or in a fume hood to avoid inhalation. Spills should be cleaned up immediately and according to the material safety data sheet (MSDS). The compound should be stored in a cool, dry place, away from direct sunlight and sources of heat. Always refer to the safety data sheet (SDS) for detailed handling and storage information.