How is 2-Methyl-2-proanyl 4-[(methylamino)methyl]-1-piperidinecarboxylate (CAS: 138022-02-3) typically synthesized?

2-Methyl-2-proanyl 4-[(methylamino)methyl]-1-piperidinecarboxylate is typically synthesized through a multistep reaction involving the coupling of 2-methyl-2-propanol and 4-(methylaminomethyl)-1-piperidinecarboxylic acid. The reaction uses catalytic amounts of a suitable base, such as triethylamine, and is carried out in an organic solvent like dichloromethane. The yield is typically around 75-80%, and the product is isolated by recrystallization.