2-Methyl-2-propanyl (2,3-dihydroxypropyl)carbamate

Basic Information

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CAS Number

137618-48-5

Molecular Formula

C8H17NO4

Molecular Weight

191.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Melting Point

60-63 °C

Boiling Point

361.6°C at 760 mmHg

Density

1.136

Flash Point

172.5°C

Refractive Index

1.475

SMILES

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CC(C)(C)OC(=O)NCC(O)CO

InChI

InChI=1S/C8H17NO4/c1-8(2,3)13-7(12)9-4-6(11)5-10/h6,10-11H,4-5H2,1-3H3,(H,9,12)

InChIKey

OWAMQHJPVUGZSB-UHFFFAOYSA-N

LogP

-0.13569999999999977

Topological Polar Surface Area

78.79 Å²

Hydrogen Bond Donor/Acceptor

3 / 5

Complexity

164

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

tert-Butyl (2,3-dihydroxypropyl)carbamate
3-(Boc-amino)-1,2-propandiole
boc-(rs)-3-amino-1,2-propanediol
tert-butyl 2,3-dihydroxypropylcarbamate
(2,3-dihydroxy-propyl)-carbamic acid tert-butyl ester
3-(Boc-amino)-1,2-propanediol
3-tert-Butoxycarbonylaminopropane-1,2-diol
471747_ALDRICH
AC1N5YPG
ACMC-20agfn
ANW-72225
t-butyl N-(2,3-dihydroxypropyl)carbamate
tert-Butyl N-(2,3-dihydroxypropyl)carbaMate
(R)-tert-Butyl (2,3-dihydroxypropyl)carbamate
Carbamic acid, (2,3-dihydroxypropyl)-, 1,1-dimethylethyl ester
(S)-tert-Butyl (2,3-dihydroxypropyl)carbamate
3-Bocamino-1,2-propanediol
N-Boc-3-amino-1,2-propanediol
OWAMQHJPVUGZSB-UHFFFA

MDL Number

MFCD01321265

FAQ

What are the physical and chemical properties of 2-Methyl-2-propanyl (2,3-dihydroxypropyl)carbamate (CAS: 137618-48-5)?

2-Methyl-2-propanyl (2,3-dihydroxypropyl)carbamate (CAS: 137618-48-5) is a solid, crystalline compound with a molecular weight of approximately 214.22 g/mol. It has a low solubility in water but is soluble in organic solvents. The compound is moderately reactive, particularly with nucleophiles, and can undergo hydrolysis under basic conditions. It is stable under normal storage conditions but should be protected from strong acids and bases.

How is 2-Methyl-2-propanyl (2,3-dihydroxypropyl)carbamate (CAS: 137618-48-5) typically synthesized?

2-Methyl-2-propanyl (2,3-dihydroxypropyl)carbamate (CAS: 137618-48-5) is typically synthesized through the reaction of 2-methyl-2-propanol and dihydroxypropylamine in the presence of a mild base such as triethylamine. The reaction is conducted under room temperature conditions, yielding a product with high selectivity and good yield.

What industries use 2-Methyl-2-propanyl (2,3-dihydroxypropyl)carbamate (CAS: 137618-48-5)?

2-Methyl-2-propanyl (2,3-dihydroxypropyl)carbamate (CAS: 137618-48-5) is utilized in the pharmaceutical industry for the synthesis of certain drugs, as well as in the polymer industry for modifying the properties of polymers. It also finds applications in the production of sensors and semiconductors due to its reactivity and functional groups.

What precautions should be taken when handling 2-Methyl-2-propanyl (2,3-dihydroxypropyl)carbamate (CAS: 137618-48-5)?

When handling 2-Methyl-2-propanyl (2,3-dihydroxypropyl)carbamate (CAS: 137618-48-5), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a fume hood to prevent inhalation. Spills should be handled according to the Material Safety Data Sheet (MSDS) guidelines, and the compound should be stored in a cool, dry place away from strong acids and bases. Always consult the latest MSDS for specific safety information.