[2',6'-bis(propan-2-yloxy)-[1,1'-biphenyl]-2-yl]dicyclohexylphosphane, {2'-amino-[1,1'-biphenyl]-2-yl}(chloro)palladium | CAS No. 1375325-68-0

[2',6'-bis(propan-2-yloxy)-[1,1'-biphenyl]-2-yl]dicyclohexylphosphane, {2'-amino-[1,1'-biphenyl]-2-yl}(chloro)palladium

Basic Information

CAS Number

1375325-68-0

Molecular Formula

C42H53ClNO2PPd

Molecular Weight

776.74 g/mol

AD

Basic Physical Properties

Melting Point

195-197 °C

CC(C)Oc1cccc(OC(C)C)c1c2ccccc2P(C3CCCCC3)C4CCCCC4.Nc1ccccc1c2ccccc2[Pd]Cl

InChI

InChI=1S/C30H43O2P.C12H10N.ClH.Pd/c1-22(2)31-27-19-13-20-28(32-23(3)4)30(27)26-18-11-12-21-29(26)33(24-14-7-5-8-15-24)25-16-9-6-10-17-25;13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;;/h11-13,18-25H,5-10,14-17H2,1-4H3;1-6,8-9H,13H2;1H;/q;;;+1/p-1

InChIKey

VPDRBFBKNSFRSS-UHFFFAOYSA-M

LogP

11.497999999999989

Topological Polar Surface Area

44.480000000000004 Ų

Hydrogen Bond Donor/Acceptor

2 / 3

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H332 Harmful if inhaled
Acute toxicity, inhalation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Storage Conditions

under inert gas (nitrogen or Argon) at 2–8 °C

Synonyms & References

English

  • Chloro(2-dicyclohexylphosphino-2',6'-di-i-propoxy-1,1'-biphenyl)(2-amino-1,1'-biphenyl-2-yl)palladium(II)
  • RuPhos Palladacycle
  • Chloro(2-dicyclohexylphosphino-2',6'-di-i-propoxy-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II)
  • RuPhos Pd G2
  • (2'-Amino-[1,1'-biphenyl]-2-yl)(dicyclohexyl(2',6'-diisopropoxy-[1,1'-biphenyl]-2-yl)phosphoranyl)palladium(III) chloride
  • chloropalladium(1+), dicyclohexyl-[2-[2,6-di(propan-2-yloxy)phenyl]phenyl]phosphane, 2-phenylaniline
  • 2nd Generation RuPhos Precatalyst
  • Chloro(2-dicyclohexylphosphino-2′,6′-diisopropoxy-1,1′-biphenyl)[2-(2′-amino-1,1′-biphenyl)]palladium(II)
  • RuPhos-Pd-G2
  • [2'-(amino-κN)[1,1'-biphenyl]-2-yl-κC][[2',6'-bis(1-methylethoxy)[1,1'-biphenyl]-2-yl]dicyclohexylphosphine-κP]chloro-Palladium
  • Chloro(2-dicyclohexylphosphino-2',6'-di-i-propoxy-1,1'-biphenyl)(2-aMino-1,1'-biphenyl-2-yl)palladiuM(II), Min. 98% [RuPhos Palladacycle]
  • Chloro(2-dicyclohexylphosphino-2',6'-diisopropoxy-1,1'-biphenyl)[2-(2'-amino-1,1'-biphenyl)]palladium(II)
  • Chloro(2-dicyclohexylphosphino-2',6'-diisopropoxy-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II)
  • [2'-(Amino)[1,1'-biphenyl]-2-yl][[2',6'-bis(1-methylethoxy)[1,1'-biphenyl]-2-yl]dicyclohexylphosphine]chloropalladium

MDL Number

MFCD20264899

FAQ

What are the physical and chemical properties of [2',6'-bis(propan-2-yloxy)-[1,1'-biphenyl]-2-yl]dicyclohexylphosphane, {2'-amino-[1,1'-biphenyl]-2-yl}(chloro)palladium (CAS: 1375325-68-0)?

This compound is a solid that crystallizes in a specific form. It has a high molecular weight and low solubility in water but is more soluble in organic solvents. It shows moderate reactivity towards nucleophiles and electrophiles. The compound is used as a catalyst in various organic synthesis reactions.

How is [2',6'-bis(propan-2-yloxy)-[1,1'-biphenyl]-2-yl]dicyclohexylphosphane, {2'-amino-[1,1'-biphenyl]-2-yl}(chloro)palladium (CAS: 1375325-68-0) typically synthesized?

This palladium complex is typically synthesized through a series of reactions involving the ligand and palladium chloride. The synthesis involves microwave-assisted techniques and requires careful handling of the precursors to ensure high yield and selectivity.

What industries use [2',6'-bis(propan-2-yloxy)-[1,1'-biphenyl]-2-yl]dicyclohexylphosphane, {2'-amino-[1,1'-biphenyl]-2-yl}(chloro)palladium (CAS: 1375325-68-0)?

This compound is primarily used in the pharmaceutical and polymer industries for the catalytic synthesis of various organic compounds. It plays a crucial role in the development of new drugs and materials with specific properties.

What precautions should be taken when handling [2',6'-bis(propan-2-yloxy)-[1,1'-biphenyl]-2-yl]dicyclohexylphosphane, {2'-amino-[1,1'-biphenyl]-2-yl}(chloro)palladium (CAS: 1375325-68-0)?

When handling this compound, wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Store it in a dry, well-ventilated area. Use a fume hood during preparation and disposal. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.

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