2-methyl-2-(3-methyl-4-((4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1H-pyrazol-1-yl)propanenitrile | CAS No. 1374828-69-9

2-methyl-2-(3-methyl-4-((4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1H-pyrazol-1-yl)propanenitrile

Basic Information

CAS Number

1374828-69-9

Molecular Formula

C14H16F3N7

Molecular Weight

339.32 g/mol

AD

Basic Physical Properties

CC1=NN(C=C1NC2=NC=C(C(=N2)NC)C(F)(F)F)C(C)(C)C#N

InChI

InChI=1S/C14H16F3N7/c1-8-10(6-24(23-8)13(2,3)7-18)21-12-20-5-9(14(15,16)17)11(19-4)22-12/h5-6H,1-4H3,(H2,19,20,21,22)

InChIKey

ZPPUMAMZIMPJGP-UHFFFAOYSA-N

Complexity

487

Safety Information

View Safety Information

Hazard Statement

H317 May cause an allergic skin reaction
Sensitization, Skin
H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

  • GNE-0877
  • 1H-​Pyrazole-​1-​acetonitrile, α,​α,​3-​trimethyl-​4-​[[4-​(methylamino)​-​5-​(trifluoromethyl)​-​2-​pyrimidinyl]​amino]​-
  • 2-Methyl-2-(3-methyl-4-((4-(methylamino)-5-(trifluoromethyl)-pyrimidin-2-yl)amino)-1H-pyrazol-1-yl)propanenitrile
  • 2-methyl-2-(3-methyl-4-((4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1H-pyrazol-1-yl)propanenitrile
  • GNE0877
  • ANGHS285FG
  • AT19318
  • AC-35917
  • SCHEMBL4561063
  • 2-methyl-2-(3-methyl-4-(4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-ylamino)-1H-pyrazol-1-yl)propanenitrile
  • compound 11 [PMID: 24354345]
  • AKOS027250747
  • GTPL9393
  • 2-methyl-2-(3-methyl-4-((4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1H-pyrazol-1-yl)propanenitrile .
  • 2-methyl-2-(3-methyl-4-{[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1H-pyrazol-1-yl)propanenitrile
  • A886471
  • GNE 0877
  • 2-methyl-2-[3-methyl-4-[[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]-1h-pyrazol-1-yl]propanenitrile
  • 2-methyl-2-(3-methyl-4-{[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}pyrazol-1-yl)propanenitrile
  • BCP09654
  • 2-Methyl-2-[3-methyl-4-[[4-(methylamino)-5-(trifluoromethyl)-2-pyrimidinyl]amino]-1-pyrazolyl]propanenitrile
  • MFCD28098661
  • DNL201
  • CCG-267909
  • HY-15796
  • SW220180-1
  • EX-A2062
  • NCGC00386334-02
  • CHEMBL3122113
  • HMS3653E18
  • UNII-ANGHS285FG

MDL Number

MFCD28098661

FAQ

What regulatory guidelines apply to 2-methyl-2-(3-methyl-4-((4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1H-pyr azol-1-yl)propanenitrile (CAS: 1374828-69-9)?

Regulatory guidelines for 2-methyl-2-(3-methyl-4-((4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1H-pyr azol-1-yl)propanenitrile (CAS: 1374828-69-9) include GHS classification, REACH regulations, and FDA/EPA requirements. GHS would classify it based on its physical and health hazards. REACH regulations would require documentation on the substance’s properties, safe handling, and environmental impact. FDA and EPA would regulate its use and disposal in pharmaceutical and chemical manufacturing contexts.

Are there alternatives to 2-methyl-2-(3-methyl-4-((4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1H-pyr azol-1-yl)propanenitrile (CAS: 1374828-69-9) in synthesis?

Yes, there are alternatives to 2-methyl-2-(3-methyl-4-((4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1H-pyr azol-1-yl)propanenitrile (CAS: 1374828-69-9) in synthesis. Common alternatives include similar pyrimidine and pyrazol structures, as well as other heterocyclic compounds. Alternative reagents such as different amines, nucleophiles, or other functional groups can be used to achieve similar reactions.

What is the market or research trend for 2-methyl-2-(3-methyl-4-((4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1H-pyr azol-1-yl)propanenitrile (CAS: 1374828-69-9)?

The market and research trends for 2-methyl-2-(3-methyl-4-((4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1H-pyr azol-1-yl)propanenitrile (CAS: 1374828-69-9) are driven by its potential applications in pharmaceuticals and agrochemicals. Research is focused on its biological activity and pharmacological properties. Market trends show increasing interest in its use as an intermediate in drug development and as a lead compound in various therapeutic areas.

How should waste containing 2-methyl-2-(3-methyl-4-((4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1H-pyr azol-1-yl)propanenitrile (CAS: 1374828-69-9) be handled?

Waste containing 2-methyl-2-(3-methyl-4-((4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1H-pyr azol-1-yl)propanenitrile (CAS: 1374828-69-9) should be handled according to hazardous waste regulations. Collection should be done in designated containers, and incineration or professional waste disposal is recommended. Environmental protection precautions include ensuring no release into water systems, and appropriate personal protective equipment should be used during handling. Compliance with local environmental protection laws is essential.

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