Ubrogepant | CAS No. 1374248-77-7

Ubrogepant

Basic Information

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CAS Number

1374248-77-7

Molecular Formula

C29H26F3N5O3

Molecular Weight

549.55 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CC1C(CC(C(=O)N1CC(F)(F)F)NC(=O)C2=CC3=C(CC4(C3)C5=C(NC4=O)N=CC=C5)N=C2)C6=CC=CC=C6

InChI

InChI=1S/C29H26F3N5O3/c1-16-20(17-6-3-2-4-7-17)11-22(26(39)37(16)15-29(30,31)32)35-25(38)19-10-18-12-28(13-23(18)34-14-19)21-8-5-9-33-24(21)36-27(28)40/h2-10,14,16,20,22H,11-13,15H2,1H3,(H,35,38)(H,33,36,40)/t16-,20-,22+,28+/m1/s1

InChIKey

DDOOFTLHJSMHLN-ZQHRPCGSSA-N

LogP

3.5306000000000015

Topological Polar Surface Area

104.29 Å²

Hydrogen Bond Donor/Acceptor

2 / 8

Complexity

1000

Synonyms & References

English

Ubrogepant
(3S)-N-[(3S,5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-3-yl]-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-carboxamide
(S)-N-((3S,5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl) piperidin-3-yl)-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxamide
MK-1602
BDBM361594
AD0O8X2QJR
EN300-20352079
(S)-N-((3S,5S,6R)-6-Methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-3-yl)-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxamide
DB15328
UBROGEPANT [INN]
UBROGEPANT [WHO-DD]
UBROGEPANT [MI]
US9833448, Example 1
AKOS040742798
MFCD28386182
Ubrogepant [USAN:INN]
CHEMBL2364638
NS00133782
Ubrogepant anhydrous
MK1602
Ubrelvy (TN)
AC-31965
(6S)-N-[(3S,5S,6R)-6-Methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-3-yl]-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxamide
CS-0011109
1374248-77-7
GTPL10176
DTXCID9082669
UBROGEPANT [ORANGE BOOK]
UNII-AD0O8X2QJR
HY-12366
Spiro(6H-cyclopenta(b)pyridine-6,3'-(3H)pyrrolo(2,3-b)pyridine)-3-carboxamide, 1',2',5,7-tetrahydro-N-((3S,5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-piperidinyl)-2'-oxo-, (3'S)-

MDL Number

MFCD28386182

FAQ

What is Ubrogepant (CAS: 1374248-77-7)?

Ubrogepant is a selective CGRP receptor antagonist used for the acute treatment of migraine with or without aura in adults. This compound has a molecular formula of C21H25N3O2 and is known for its analgesic properties.

What are the main uses of Ubrogepant (CAS: 1374248-77-7)?

Ubrogepant is primarily used in the acute treatment of migraine with or without aura. It is a prescription medication that provides fast relief to migraine sufferers by blocking the calcitonin gene-related peptide (CGRP), a key player in migraine pain.

Is Ubrogepant (CAS: 1374248-77-7) safe?

Ubrogepant is considered safe when used as prescribed. However, it is important to follow the doctor's instructions and be aware of potential side effects such as nausea, dizziness, and dysgeusia. Patients should avoid driving or operating heavy machinery if experiencing dizziness.

How should Ubrogepant (CAS: 1374248-77-7) be stored?

Ubrogepant should be stored at room temperature (15°C to 30°C or 59°F to 86°F), away from direct sunlight and moisture. It should be kept in a tightly closed container and protected from light and excessive humidity to maintain its efficacy.