4-Chloro-6-ethyl-5-fluoropyrimidine

Basic Information

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CAS Number

137234-74-3

Molecular Formula

C6H6ClFN2

Molecular Weight

160.58 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

210.9°C at 760 mmHg

Flash Point

81ºC

Refractive Index

1.4962

SMILES

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CCC1=C(C(=NC=N1)Cl)F

InChI

InChI=1S/C6H6ClFN2/c1-2-4-5(8)6(7)10-3-9-4/h3H,2H2,1H3

InChIKey

LKTGVRWVTAJGMS-UHFFFAOYSA-N

LogP

1.8315000000000001

Topological Polar Surface Area

25.78 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

112

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class 8 Class 8

Synonyms & References

English

PB10473
4-Chloro-6-ethyl-5-fluoropyrimidine, AldrichCPR
Q-102789
4-Chloro-6-ethyl-5-fluoro-pyrimidine
LKTGVRWVTAJGMS-UHFFFAOYSA-N
AS-15052
CS-B1291
EC 604-010-1
FT-0643264
SY011522
4-Chloro-6-ethyl-5-fluoropyrimidine
F0001-0470
AC-4747
137234-74-3
SCHEMBL372414
DTXSID30587753
Z1198174780
EN300-102307
BCP04247
MFCD07782087
4-chloro-6-ethyl-5-fluoro pyrimidine
AKOS005063655
NS00004637
PYRIMIDINE, 4-CHLORO-6-ETHYL-5-FLUORO-
6-CHLORO-4-ETHYL-5-FLUORO-1,6-DIHYDROPYRIMIDINE
4-chloro-6-ethyl-5-flouropyrimidine
4-Chloro-2-methylsulfanyl-pyrimidine-5-carbonitrile
Voriconazole Intermediate II
PYRIMIDINE,4-CHLORO-6-ETHYL-5-FLUORO
Pyrimidine,4-chloro-6-ethyl-5-fluoro-
PubChem7037

MDL Number

MFCD07782087

Customs Code

2933599090

FAQ

What is 4-Chloro-6-ethyl-5-fluoropyrimidine (CAS: 137234-74-3)?

4-Chloro-6-ethyl-5-fluoropyrimidine (CAS: 137234-74-3) is a synthetic organic compound with the chemical formula C8H8ClFN2O. It is a pyrimidine derivative containing chlorine, fluorine, and ethyl groups. This compound is known for its stability under normal conditions and is commonly used in the development of pharmaceuticals and chemical research due to its reactivity and structural versatility.

What are the main uses of 4-Chloro-6-ethyl-5-fluoropyrimidine (CAS: 137234-74-3)?

4-Chloro-6-ethyl-5-fluoropyrimidine (CAS: 137234-74-3) is primarily used in pharmaceutical research as a building block for drug development, particularly in the synthesis of antifungal and antiviral agents. It also finds applications in organic chemistry for creating derivatives and in industrial processes for chemical intermediates and functional materials.

Is 4-Chloro-6-ethyl-5-fluoropyrimidine (CAS: 137234-74-3) safe?

4-Chloro-6-ethyl-5-fluoropyrimidine (CAS: 137234-74-3) is generally considered safe when handled properly, but it may have toxic effects if ingested or inhaled in large quantities. Protective measures such as gloves, goggles, and a fume hood are recommended during use. It should be kept away from sources of ignition and stored in accordance with standard chemical safety guidelines.

How should 4-Chloro-6-ethyl-5-fluoropyrimidine (CAS: 137234-74-3) be stored?

4-Chloro-6-ethyl-5-fluoropyrimidine (CAS: 137234-74-3) should be stored in a cool, dry, and well-ventilated area, away from light. It is typically kept in a sealed container at a temperature below 25°C and in a humidity-controlled environment to maintain stability and prevent degradation. Avoid exposure to air and moisture during storage.