(3R)-3-Fluoropyrrolidine hydrochloride (1:1)

Basic Information

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CAS Number

136725-55-8

Molecular Formula

C4H9ClFN

Molecular Weight

125.57 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

179-186 °C

Boiling Point

91 ºC at 760 mmHg

Flash Point

8.8 ºC

SMILES

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C1CNCC1F.Cl

InChI

InChI=1S/C4H8FN.ClH/c5-4-1-2-6-3-4;/h4,6H,1-3H2;1H/t4-;/m1./s1

InChIKey

LENYOXXELREKGZ-PGMHMLKASA-N

LogP

0.7396000000000003

Topological Polar Surface Area

12.03 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

46.8

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Sensitiveness

Moisture Sensitive

Synonyms & References

English

Pyrrolidine,3-fluoro-,hydrochloride(1:1),(3S)-
(R)-3-fluoropyrrolidine hydrochloride salt
J-502094
(R)-3-fluoropyrrolidin hydrochloride
(3R)-3-fluoropyrrolidine hydrochloride
Pyrrolidine, 3-fluoro-, hydrochloride (1:1), (3R)-
(3R)-3-fluoropyrrolidine,hydrochloride;
3-(R)-fluoropyrrolidine hydrochloride
A25560
MFCD04038717
(R)-3-Fluoropyrrolidine (hydrochloride)
C4H9ClFN
LENYOXXELREKGZ-PGMHMLKASA-N
(R)(-)3-fluoropyrrolidine hydrochloride
DTXSID10374663
(R)-(-)-3-Fluoropyrrolidine hydrochloride, 97%
(r)-3-fluoropyrrolidine hydrochloride
136725-55-8
AKOS005063428
(S)-(+)-3-Fluoropyrrolidine HCl
(R)-3-fluoropyrrolidin-1-ium chloride
(R)-(-)-3-Fluoropyrrolidine hydrochloride
BCP14098
HY-40421
AM20080271
(3R)-3-fluoropyrrolidine;hydrochloride
(R)-(-)-3-FLUOROPYRROLIDINE HCL
(R)-3-fluoro-pyrrolidine hydrochloride
CS-M3463
(R)-3-fluoropyrrolidine HCl
(r)-(-)-3-fluoropyrrolidinehydrochloride

MDL Number

MFCD04038717

Customs Code

2933990090

FAQ

What regulatory guidelines apply to (3R)-3-Fluoropyrrolidine hydrochloride (CAS: 136725-55-8)?

The (3R)-3-Fluoropyrrolidine hydrochloride (CAS: 136725-55-8) is subject to various global regulatory guidelines. In the European Union, it falls under REACH regulations, which require manufacturers to register and assess the safety of chemicals. In the United States, it is under the purview of the EPA and FDA for environmental and food safety, respectively. Users must ensure compliance with material safety data sheet (MSDS) guidelines, particularly regarding its handling, storage, and transportation to avoid hazardous exposure and environmental pollution.

Are there alternatives to (3R)-3-Fluoropyrrolidine hydrochloride (CAS: 136725-55-8) in synthesis?

Alternative reagents to (3R)-3-Fluoropyrrolidine hydrochloride (CAS: 136725-55-8) include other fluorinated pyrrolidines and their respective hydrochlorides. Isomers such as (3S)-3-Fluoropyrrolidine hydrochloride and non-fluorinated analogs like 3-Pyrrolidinol can serve as alternatives depending on the specific needs of the synthesis. These alternatives are often chosen based on their availability, cost, and reactivity.

What is the market or research trend for (3R)-3-Fluoropyrrolidine hydrochloride (CAS: 136725-55-8)?

The (3R)-3-Fluoropyrrolidine hydrochloride (CAS: 136725-55-8) market is growing due to its applications in pharmaceuticals and fine chemicals. Research trends indicate increasing interest in its use as a precursor in drug synthesis, particularly in the development of new antifungal and antiviral drugs. Additionally, its potential in polymer chemistry and material science is being explored, driven by its unique physical and chemical properties.

How should waste containing (3R)-3-Fluoropyrrolidine hydrochloride (CAS: 136725-55-8) be handled?

Waste containing (3R)-3-Fluoropyrrolidine hydrochloride (CAS: 136725-55-8) should be collected in appropriate containers labeled with the hazardous material symbol. For proper disposal, the waste should undergo incineration or professional chemical waste disposal services. Environmental precautions include ensuring that the waste does not enter water bodies or soil, and all handling should be done in a fume hood under proper personal protective equipment to minimize exposure risks.